MIA3

Gene Symbol MIA3
Entrez Gene 375056
Alt Symbol ARNT, D320, TANGO, TANGO1, UNQ6077
Species Human
Gene Type protein-coding
Description melanoma inhibitory activity family, member 3
Other Description C219-reactive peptide|melanoma inhibitory activity protein 3|transport and Golgi organization protein 1
Swissprots Q3S4X3 A8K2S0 Q92580 Q8N8M5 Q6UVY8 Q5JRB2 Q5JRA6 Q5JRA5 Q5JRB0 Q86Y60 A8MT13 Q14083 A8MT05 Q5JRB1 B7Z430
Accessions CAH05393 EAW93267 Q5JRA6 AK025122 AK025506 AK026489 AK096526 BAC04810 AK290335 BAF83024 AK296712 BAH12416 AK307412 AX775845 CAE11622 AY359091 AAQ89449 BC031805 BC047116 AAH47116 BG429750 BP423646 CK724924 D87742 BAA13448 DA040423 DQ166034 AAZ95512 L34688 AAB00324 XM_005273121 XP_005273178 XM_006711304 XP_006711367 XM_011509513 XP_011507815 NM_001300867 NP_001287796 NM_198551 NP_940953
Function Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. May participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. {ECO:0000269|PubMed:19269366}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:19269366}; Single-pass type I membrane protein {ECO:0000269|PubMed:19269366}. Note=Localizes at endoplasmic reticulum exit sites. After loading of COL7A1 into transport carriers, it is not incorporated into COPII carriers and remains in the endoplasmic reticulum membrane.
Tissue Specificity Broadly expressed, except in bone marrow and peripheral blood mononuclear cells. Down-regulated in melanoma tissue. {ECO:0000269|PubMed:15183315, ECO:0000269|PubMed:17044017}.

MIA3 (H-156) - sc-366098 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MIA3 (H-156): sc-366098. Western blot analysis of MIA3 expression in HeLa (A), Caki-1 (B) and K-562 (C) whole cell lysates.

MIA3 (C-5) - sc-393916 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MIA3 (C-5): sc-393916. Western blot analysis of MIA3 expression in Caki-1 (A) and K-562 (B) whole cell lysates.

MIA3 (N-13) - sc-161853 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MIA3 (P-15) - sc-161854 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-MIA3 antibody - ab97881 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MIA3 antibody (ab97881) at 1/1000 dilutionLane 1 : A549 whole cell lysateLane 2 : Hep G2 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-TANGO / MIA3 Antibody IHC-plus™ - LS-B4210 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-MIA3 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4210 concentration 10 ug/ml.

MIA3 Antibody - NBP2-33770 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MIA3 Antibody [NBP2-33770] - Analysis in human cell line U-251 MG.

MIA3 Antibody - NBP2-34160 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: MIA3 Antibody [NBP2-34160] - Immunofluorescent staining of human cell line U-251 MG shows localization to vesicles.

ARNT/HIF-1 beta Antibody (H1beta234) [7C] - NB100-124V2 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone H1beta234

ARNT/HIF-1 beta Antibody (H1beta234) [PerCP] - NB100-124PCP from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone H1beta234

ARNT/HIF-1 beta Antibody (H1beta234) [DyLight 680] - NB100-124FR from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone H1beta234

ARNT/HIF-1 beta Antibody (H1beta234) [DyLight 405LS] - NB100-124V3 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone H1beta234

ARNT/HIF-1 beta Antibody (H1beta234) [Allophycocyanin] - NB100-124APC from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone H1beta234

ARNT/HIF-1 beta Antibody (H1beta234) [PE] - NB100-124PE from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone H1beta234

ARNT/HIF-1 beta Antibody (H1beta234) [DyLight 755] - NB100-124IR from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone H1beta234

ARNT/HIF-1 beta Antibody (H1beta234) [DyLight 350] - NB100-124UV from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Mouse
Clonality Monoclonal
Clone H1beta234

Anti-MIA3 antibody produced in rabbit - HPA055922 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MIA3: <B>Cat. No. HPA055922</B>: Immunohistochemical staining of Human bone marrow shows strong cytoplasmic positivity in subset of hematopoietic cells.

Anti-MIA3 antibody produced in rabbit - HPA056816 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MIA3: <B>Cat. No. HPA056816</B>: Immunohistochemical staining of Human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.

ARNT Antibody - middle region (ARP36562_P050) - ARP36562_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

arnt antibody - zf125404 from GeneTex

Host Rabbit
Clonality Polyclonal

arnt antibody - zf125405 from GeneTex

Host Rabbit
Clonality Polyclonal

arnt antibody - zf125406 from GeneTex

Host Rabbit
Clonality Polyclonal

MIA3 antibody [N1], N-term - GTX101827 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-MIA3 antibody [N1], N-term used in Western blot. GTX101827
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