| Gene Symbol |
FLOT1
|
| Entrez Gene |
10211
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
flotillin 1
|
| Other Description |
flotillin-1|integral membrane component of caveolae
|
| Swissprots |
O75955 Q9UNV8 Q9UHW1 B4DVY7 Q969J8
|
| Accessions |
BAB63320 BAC54934 BAE78620 BAF31269 EAX03325 EAX03326 EAX03327 O75955 AF085357 AAD40192 AF089750 AAC35387 AF117234 AAF17215 AK000816 AK222530 BAD96250 AK301291 BAG62849 BC001146 AAH01146 BC128154 AAI28155 BT007077 AAP35740 CR456946 CAG33227 DQ890639 ABM92256 DQ893815 ABM84741 XM_005248780 XP_005248837 XM_005248781 XP_005248838 XM_005272759 XP_005272816 XM_005272760 XP_005272817 XM_005274909 XP_005274966 XM_005274910 XP_005274967 XM_005275335 XP_005275392 XM_005275336 XP_005275393 XM_005275502 XP_005275559 XM_005275503 XP_005275560 XM_006714947 XP_006715010 XM_006725465 XP_006725528 XM_006725672 XP_006725735 XM_006725971 XP_006726034 XM_006726072 XP_006726135 NM_005803 NP_005794
|
| Function |
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
|
| Subcellular Location |
Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Melanosome. Endosome. Note=Membrane-associated protein of caveolae. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
|
| Top Pathways |
Insulin signaling pathway
|
![Western Blot: Flotillin-1 Overexpression Lysate (Adult Normal) [NBL1-10769] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Flotillin-1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2713_Flotillin-1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10769-img0003.jpg)