CD1E

Gene Symbol CD1E
Entrez Gene 913
Alt Symbol CD1A, R2
Species Human
Gene Type protein-coding
Description CD1e molecule
Other Description CD1E antigen, e polypeptide|R2G1|T-cell surface glycoprotein CD1e, membrane-associated|differentiation antigen CD1-alpha-3|hCD1e|leukocyte differentiation antigen|thymocyte antigen CD1E
Swissprots Q5TDK4 Q712F0 Q712E9 Q712E6 E7EP01 P15812 Q96TD0 Q712E7 B4DZV3 Q5TDK6 Q5TDK8 Q96TD1 Q712E4 Q712F5 Q9UMM1 Q5TDJ9 Q712F3 Q712F2 Q5TDK5 Q5TDL1 Q9Y5M3 Q712E5 Q5TDK3 Q712F4 Q712E8 Q712F1
Accessions AAA51937 AAD37582 CAA33100 CAB82829 CAC07175 EAW52828 EAW52829 EAW52830 EAW52831 EAW52832 EAW52833 EAW52834 EAW52835 EAW52836 EAW52837 EAW52838 EAW52839 EAW52840 P15812 AA283335 AA354546 AJ289111 CAB93150 AJ289112 CAB93151 AJ289113 CAB93152 AJ289114 CAB93153 AJ289115 CAB93154 AJ289116 CAB93155 AJ289117 CAB93156 AJ289118 CAB93157 AJ289119 CAB93158 AJ289120 CAB93159 AJ289121 CAB93160 AJ289122 CAB93161 AK303088 BAG64199 AK303108 BAG64215 AK303217 BAG64304 AK303233 BAG64319 AK303542 BAG64568 AK310567 AK311643 BC131693 AAI31694 DA827206 DC406237 X79517 CAA56053 X79518 CAA56054 X79519 CAA56055 XM_011510133 XP_011508435 XM_011510134 XP_011508436 XM_011510135 XP_011508437 NM_001042583 NP_001036048 NM_001042584 NP_001036049 NM_001042585 NP_001036050 NM_001042586 NP_001036051 NM_001042587 NP_001036052 NM_001185107 NP_001172036 NM_001185108 NP_001172037 NM_001185110 NP_001172039 NM_001185112 NP_001172041 NM_001185113 NP_001172042 NM_001185114 NP_001172043 NM_001185115 NP_001172044 NM_030893 NP_112155
Function T-cell surface glycoprotein CD1e, soluble binds diacetylated lipids, including phosphatidyl inositides and diacylated sulfoglycolipids, and is required for the presentation of glycolipid antigens on the cell surface. The membrane- associated form is not active. {ECO:0000269|PubMed:10948205, ECO:0000269|PubMed:16311334, ECO:0000269|PubMed:21788486}.
Subcellular Location T-cell surface glycoprotein CD1e, membrane- associated: Golgi apparatus membrane; Single-pass type I membrane protein. Early endosome. Late endosome. Note=Predominantly localized in the trans-Golgi network in immature dendritic cells, and as a cleaved, soluble protein in the lysosome lumen of mature dendritic cells.
Tissue Specificity Expressed on cortical thymocytes, dendritic cells, Langerhans cells, on certain T-cell leukemias, and in various other tissues. {ECO:0000269|PubMed:10948205}.
Top Pathways Hematopoietic cell lineage

CD1E CRISPR/Cas9 KO Plasmid (h) - sc-416725 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD1E HDR Plasmid (h) - sc-416725-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD1E Double Nickase Plasmid (h) - sc-416725-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD1E Double Nickase Plasmid (h2) - sc-416725-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD1E CRISPR Activation Plasmid (h) - sc-416725-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD1E CRISPR Activation Plasmid (h2) - sc-416725-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD1E Lentiviral Activation Particles (h) - sc-416725-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD1E Lentiviral Activation Particles (h2) - sc-416725-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CD1E siRNA (h) - sc-78837 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD1E shRNA Plasmid (h) - sc-78837-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD1E shRNA (h) Lentiviral Particles - sc-78837-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CD1a RNAi - H00000909-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU044831 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5693 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5693 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05653 from Sigma-Aldrich

Category miRNA

CD1E siRNA (Human) - CRH0642 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD1E - MBS8208566 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CD1 (NM_030893.3) - SHH258429 from Creative biogene

Category siRNA
Species Reactivities Human

Human CD1E siRNA - orb261144 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CD1E shRNA Plasmid (Human) - CHH0642 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CD1E miRNA 3'UTR clone - MiUTR4H-TG10833 from Creative biogene

Species Reactivities Human
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