ECE1

Gene Symbol ECE1
Entrez Gene 1889
Alt Symbol ECE
Species Human
Gene Type protein-coding
Description endothelin converting enzyme 1
Other Description ECE-1|endothelin-converting enzyme 1
Swissprots Q17RN5 Q9Y501 B4E291 Q9UJQ6 P42892 Q14217 Q5THM5 Q9UPF4 A8K3P1 Q2Z2K8 Q5THM8 Q5THM7 Q58GE7 Q9UPM4
Accessions AAD08993 AAD21221 AAX35820 CAA02807 CAA63015 CAA63016 EAW94957 EAW94958 EAW94959 EAW94960 EAW94961 EAW94962 EAW94963 EAW94964 EAW94965 EAW94966 P42892 AB031742 BAA83687 AJ130828 CAB46443 AK123231 AK290656 BAF83345 AK296486 BAG59124 AK304167 BAG65053 AK309677 BC023596 BC041647 BC053342 BC063506 BC077076 BC106022 BC117256 AAI17257 BC126257 AAI26258 BP234532 BP337331 BU733112 BX648351 CN298523 CN298525 D43698 BAA07800 D49471 BAA08442 DA436879 DA445355 DA445401 DB290492 HQ258359 ADR83113 X98272 CAA66922 Z35307 CAA84548 XM_006710398 XP_006710461 XM_011540872 XP_011539174 XM_011540873 XP_011539175 NM_001113347 NP_001106818 NM_001113348 NP_001106819 NM_001113349 NP_001106820 NM_001397 NP_001388
Function Converts big endothelin-1 to endothelin-1. {ECO:0000269|PubMed:9396733}.
Subcellular Location Cell membrane; Single-pass type II membrane protein.
Tissue Specificity All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma; isoforms A and C in liver, testis and small intestine; isoform B, C and D in endothelial cells and umbilical vein smooth muscle cells; isoforms C and D in saphenous vein cells, and isoform C in kidney. {ECO:0000269|PubMed:10491078, ECO:0000269|PubMed:9396733}.

ECE-1 (A-6) - sc-376017 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ECE-1 (A-6): sc-376017. Western blot analysis of ECE-1 expression in HUV-EC-C whole cell lysate.

ECE-1 (C-12) - sc-376018 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ECE-1 (C-12): sc-376018. Western blot analysis of ECE-1 expression in HUV-EC-C whole cell lysate.

ECE-1 (F-16) - sc-27557 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ECE-1 (S-13) - sc-27558 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ECE-1 (H-60) - sc-25841 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ECE-1 (H-60): sc-25841. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lung tissue showing cytoplasmic and nuclear staining of macrophages and pneumocytes.

Anti-ECE1 antibody - ab189843 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ECE1 antibody (ab189843) at 1/500 dilutionLane 1 : Mouse liver tissue extractLane 2 : Mouse lung tissue extract

Anti-ECE1 antibody - ab93117 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab93117 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab93117, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM

Anti-ECE-1 Antibody (aa528-556, AP) - LS-C222303 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (aa528-556, APC) - LS-C222304 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (aa528-556, FITC) - LS-C222306 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (aa528-556, Biotin) - LS-C222307 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (aa528-556, PE) - LS-C222310 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (aa528-556, Azide-free, HRP) - LS-C222309 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (APC) - LS-C225450 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (FITC) - LS-C225451 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (AP) - LS-C225448 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (Azide-free, HRP) - LS-C225453 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (Biotin) - LS-C225452 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (PE) - LS-C225454 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (aa326-577, Biotin) - LS-C297784 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (aa326-577, FITC) - LS-C301741 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (aa469-721, Biotin) - LS-C297783 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (aa469-721, FITC) - LS-C301739 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (aa535-564) - LS-C321007 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ECE-1 Antibody (Internal) - LS-C327317 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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