Gene Symbol |
MMRN2
|
Entrez Gene |
79812
|
Alt Symbol |
EMILIN-3, EMILIN3, ENDOGLYX-1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
multimerin 2
|
Other Description |
EMILIN-like protein EndoGlyx-1|elastin microfibril interface located protein 3|elastin microfibril interfacer 3|endoGlyx-1 p125/p140 subunit|multimerin-2
|
Swissprots |
Q504V7 Q9H8L6 Q6P2N2
|
Accessions |
EAW80319 Q9H8L6 AK023527 BAB14599 AK293822 BAG57226 AK304727 BAG65490 AK308401 BC064415 AAH64415 BC072456 BC094744 AAH94744 BM673127 DC416005 W38498 XM_005270153 XP_005270210 XM_006717970 XP_006718033 NM_024756 NP_079032
|
Function |
Inhibits endothelial cells motility and acts as a negative regulator of angiogenesis; it downregulates KDR activation by binding VEGFA. {ECO:0000269|PubMed:22020326}.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:11559704}.
|
Tissue Specificity |
Endothelium. {ECO:0000269|PubMed:11559704}.
|