Gene Symbol | SUB1 |
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Entrez Gene | 10923 |
Alt Symbol | P15, PC4, p14 |
Species | Human |
Gene Type | protein-coding |
Description | SUB1 homolog (S. cerevisiae) |
Other Description | activated RNA polymerase II transcription cofactor 4|activated RNA polymerase II transcriptional coactivator p15|positive cofactor 4 |
Swissprots | Q96L29 P53999 |
Accessions | CBX54570 EAX10793 EAX10794 EAX10795 EAX10796 P53999 AB209285 BAD92522 AK294124 BAH11676 AK307268 AK311754 BAG34697 BC009610 AAH09610 BC010537 AAH10537 BC018189 AAH18189 BC022339 AAH22339 BC063402 BC070171 BC071655 BC105972 AAI05973 BX472106 BX537584 CR456902 CAG33183 U12979 AAA20980 X79805 CAA56200 XM_011513943 XP_011512245 XM_011513944 XP_011512246 NM_006713 NP_006704 |
Function | General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA). {ECO:0000269|PubMed:16605275, ECO:0000269|PubMed:16689930, ECO:0000269|PubMed:7628453, ECO:0000269|PubMed:8062391, ECO:0000269|PubMed:8062392, ECO:0000269|PubMed:9360603, ECO:0000269|PubMed:9482861}. |
Subcellular Location | Nucleus. |
SUB1-Over-expression-Lysate - LY13763a from Abgent, a WuXi AppTec company
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PC4 293T Cell Transient Overexpression Lysate(Denatured) - H00010923-T01 from Acris Antibodies
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SUB1 293 Cell Lysate - 401786 from ABBIOTEC
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SUB1 Overexpression Lysate (Denatured) - H00010923-T01 from Novus Biologicals
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SUB1 Overexpression Lysate (Native) - NBL1-16593 from Novus Biologicals
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Positive cofactor 4 (h2): 293 Lysate - sc-112271 from Santa Cruz Biotechnology
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Positive cofactor 4 (h3): 293 Lysate - sc-113077 from Santa Cruz Biotechnology
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SUB1 Over-expression Lysate Product - GWB-68689A from Genway Biotech
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Panoply™ Human SUB1 Knockdown Stable Cell Line - CSC-DC015377 from Creative biogene
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