Gene Symbol | SUB1 |
---|---|
Entrez Gene | 10923 |
Alt Symbol | P15, PC4, p14 |
Species | Human |
Gene Type | protein-coding |
Description | SUB1 homolog (S. cerevisiae) |
Other Description | activated RNA polymerase II transcription cofactor 4|activated RNA polymerase II transcriptional coactivator p15|positive cofactor 4 |
Swissprots | Q96L29 P53999 |
Accessions | CBX54570 EAX10793 EAX10794 EAX10795 EAX10796 P53999 AB209285 BAD92522 AK294124 BAH11676 AK307268 AK311754 BAG34697 BC009610 AAH09610 BC010537 AAH10537 BC018189 AAH18189 BC022339 AAH22339 BC063402 BC070171 BC071655 BC105972 AAI05973 BX472106 BX537584 CR456902 CAG33183 U12979 AAA20980 X79805 CAA56200 XM_011513943 XP_011512245 XM_011513944 XP_011512246 NM_006713 NP_006704 |
Function | General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA). {ECO:0000269|PubMed:16605275, ECO:0000269|PubMed:16689930, ECO:0000269|PubMed:7628453, ECO:0000269|PubMed:8062391, ECO:0000269|PubMed:8062392, ECO:0000269|PubMed:9360603, ECO:0000269|PubMed:9482861}. |
Subcellular Location | Nucleus. |
Positive cofactor 4 CRISPR/Cas9 KO Plasmid (h) - sc-403272 from Santa Cruz Biotechnology
|
||||||||
Positive cofactor 4 HDR Plasmid (h) - sc-403272-HDR from Santa Cruz Biotechnology
|
||||||||
Positive cofactor 4 Double Nickase Plasmid (h) - sc-403272-NIC from Santa Cruz Biotechnology
|
||||||||
Positive cofactor 4 Double Nickase Plasmid (h2) - sc-403272-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Positive cofactor 4 CRISPR Activation Plasmid (h) - sc-403272-ACT from Santa Cruz Biotechnology
|
||||||||
Positive cofactor 4 CRISPR Activation Plasmid (h2) - sc-403272-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Positive cofactor 4 Lentiviral Activation Particles (h) - sc-403272-LAC from Santa Cruz Biotechnology
|
||||||||
Positive cofactor 4 Lentiviral Activation Particles (h2) - sc-403272-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Positive cofactor 4 siRNA (h) - sc-38583 from Santa Cruz Biotechnology
|
||||||||
Positive cofactor 4 shRNA Plasmid (h) - sc-38583-SH from Santa Cruz Biotechnology
|
||||||||
Positive cofactor 4 shRNA (h) Lentiviral Particles - sc-38583-V from Santa Cruz Biotechnology
|
||||||||
SUB1 RNAi - H00010923-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU031131 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN20801 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20801 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR07434 from Sigma-Aldrich
|
||||||||
SUB1 siRNA (Human) - CRH7450 from Cohesion Biosciences
|
||||||||
SUB1 - MBS8213900 from MyBioSource
|
||||||||
Positive cofactor 4 CRISPR/Cas9 KO Plasmid (h2) - sc-403272-KO-2 from Santa Cruz Biotechnology
|
||||||||
Positive cofactor 4 HDR Plasmid (h2) - sc-403272-HDR-2 from Santa Cruz Biotechnology
|
||||||||
Human SUB1 siRNA - orb267952 from Biorbyt
|
||||||||
SUB1 shRNA Plasmid (Human) - CHH7450 from Cohesion Biosciences
|
||||||||
SUB1 miRNA 3'UTR clone - MiUTR4H-TG08652 from Creative biogene
|