Gene Symbol |
OR1D2
|
Entrez Gene |
4991
|
Alt Symbol |
OLFR1, OR17-4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
olfactory receptor, family 1, subfamily D, member 2
|
Other Description |
olfactory receptor 17-4|olfactory receptor 1D2|olfactory receptor OR17-6|olfactory receptor-like protein HGMP07E
|
Swissprots |
Q9UM78 Q6IFL8 Q96RA4 P34982
|
Accessions |
AAA18343 AAC99554 AAF37310 AAK95020 CAA46687 DAA04642 EAW90524 P34982 BC069552 AAH69552 BC106735 AAI06736 BC106736 AAI06737 NM_002548 NP_002539
|
Function |
Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception. {ECO:0000269|PubMed:12663925, ECO:0000269|PubMed:15458659, ECO:0000269|PubMed:16820410}.
|
Subcellular Location |
Cell membrane {ECO:0000269|PubMed:16820410}; Multi-pass membrane protein {ECO:0000269|PubMed:16820410}. Note=In spermatazoa is localized in the midpiece and is translocated to the head region upon receptor stimulation with bourgeonal.
|
Tissue Specificity |
Expressed in testis. Expressed in spermatozoa (at protein level). Expressed in olfactory epithelium. {ECO:0000269|PubMed:12663925, ECO:0000269|PubMed:15458659, ECO:0000269|PubMed:16820410}.
|
Top Pathways |
Olfactory transduction
|