Gene Symbol | OR1D2 |
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Entrez Gene | 4991 |
Alt Symbol | OLFR1, OR17-4 |
Species | Human |
Gene Type | protein-coding |
Description | olfactory receptor, family 1, subfamily D, member 2 |
Other Description | olfactory receptor 17-4|olfactory receptor 1D2|olfactory receptor OR17-6|olfactory receptor-like protein HGMP07E |
Swissprots | Q9UM78 Q6IFL8 Q96RA4 P34982 |
Accessions | AAA18343 AAC99554 AAF37310 AAK95020 CAA46687 DAA04642 EAW90524 P34982 BC069552 AAH69552 BC106735 AAI06736 BC106736 AAI06737 NM_002548 NP_002539 |
Function | Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception. {ECO:0000269|PubMed:12663925, ECO:0000269|PubMed:15458659, ECO:0000269|PubMed:16820410}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:16820410}; Multi-pass membrane protein {ECO:0000269|PubMed:16820410}. Note=In spermatazoa is localized in the midpiece and is translocated to the head region upon receptor stimulation with bourgeonal. |
Tissue Specificity | Expressed in testis. Expressed in spermatozoa (at protein level). Expressed in olfactory epithelium. {ECO:0000269|PubMed:12663925, ECO:0000269|PubMed:15458659, ECO:0000269|PubMed:16820410}. |
Top Pathways | Olfactory transduction |
OR1D2 CRISPR/Cas9 KO Plasmid (h) - sc-410916 from Santa Cruz Biotechnology
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OR1D2 HDR Plasmid (h) - sc-410916-HDR from Santa Cruz Biotechnology
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OR1D2 Double Nickase Plasmid (h) - sc-410916-NIC from Santa Cruz Biotechnology
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OR1D2 Double Nickase Plasmid (h2) - sc-410916-NIC-2 from Santa Cruz Biotechnology
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OR1D2 CRISPR Activation Plasmid (h) - sc-410916-ACT from Santa Cruz Biotechnology
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OR1D2 CRISPR Activation Plasmid (h2) - sc-410916-ACT-2 from Santa Cruz Biotechnology
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OR1D2 Lentiviral Activation Particles (h) - sc-410916-LAC from Santa Cruz Biotechnology
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OR1D2 Lentiviral Activation Particles (h2) - sc-410916-LAC-2 from Santa Cruz Biotechnology
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OR1D2 siRNA (h) - sc-93893 from Santa Cruz Biotechnology
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OR1D2 shRNA Plasmid (h) - sc-93893-SH from Santa Cruz Biotechnology
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OR1D2 shRNA (h) Lentiviral Particles - sc-93893-V from Santa Cruz Biotechnology
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OR1D2 RNAi - H00004991-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN15814 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15814 from Sigma-Aldrich
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OR1D2 siRNA (Human) - CRH3311 from Cohesion Biosciences
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shRNA set against Human OR1D2 (NM_002548.2) - SHH367048 from Creative biogene
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OR1D2 shRNA Plasmid (Human) - CHH3311 from Cohesion Biosciences
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OR1D2 miRNA 3'UTR clone - MiUTR4H-TG06265 from Creative biogene
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