| Gene Symbol |
ATP1B4
|
| Entrez Gene |
23439
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATPase, Na+/K+ transporting, beta 4 polypeptide
|
| Other Description |
Na,K-ATPase beta m-subunit|X,K-ATPase beta-m subunit|protein ATP1B4|x/potassium-transporting ATPase subunit beta-m
|
| Swissprots |
Q9UN41 Q17RR0 Q9UN42
|
| Accessions |
EAX11885 EAX11886 Q9UN42 AA436959 AF158383 AAD49692 AF158384 AAD49693 AK309999 BC117227 AAI17228 BC143404 AAI43405 BC143406 AAI43407 BC143407 AAI43408 DA895576 HQ258396 ADR83150 NM_001142447 NP_001135919 NM_012069 NP_036201
|
| Function |
May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit. {ECO:0000269|PubMed:17592128}.
|
| Subcellular Location |
Nucleus inner membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Detected in nuclear envelops. {ECO:0000269|PubMed:14656723, ECO:0000269|PubMed:17592128}.
|
| Tissue Specificity |
Highly expressed in skeletal muscle and at a lower level in heart. {ECO:0000269|PubMed:10456317}.
|
| Top Pathways |
Salivary secretion, Cardiac muscle contraction, Aldosterone-regulated sodium reabsorption, cAMP signaling pathway, Thyroid hormone synthesis
|
