Gene Symbol | ATP1B4 |
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Entrez Gene | 23439 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, Na+/K+ transporting, beta 4 polypeptide |
Other Description | Na,K-ATPase beta m-subunit|X,K-ATPase beta-m subunit|protein ATP1B4|x/potassium-transporting ATPase subunit beta-m |
Swissprots | Q9UN41 Q17RR0 Q9UN42 |
Accessions | EAX11885 EAX11886 Q9UN42 AA436959 AF158383 AAD49692 AF158384 AAD49693 AK309999 BC117227 AAI17228 BC143404 AAI43405 BC143406 AAI43407 BC143407 AAI43408 DA895576 HQ258396 ADR83150 NM_001142447 NP_001135919 NM_012069 NP_036201 |
Function | May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit. {ECO:0000269|PubMed:17592128}. |
Subcellular Location | Nucleus inner membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Detected in nuclear envelops. {ECO:0000269|PubMed:14656723, ECO:0000269|PubMed:17592128}. |
Tissue Specificity | Highly expressed in skeletal muscle and at a lower level in heart. {ECO:0000269|PubMed:10456317}. |
Top Pathways | Salivary secretion, Cardiac muscle contraction, Aldosterone-regulated sodium reabsorption, cAMP signaling pathway, Thyroid hormone synthesis |
Na + /K + -ATPase β4 siRNA (h) - sc-90979 from Santa Cruz Biotechnology
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Na + /K + -ATPase β4 shRNA Plasmid (h) - sc-90979-SH from Santa Cruz Biotechnology
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Na + /K + -ATPase β4 shRNA (h) Lentiviral Particles - sc-90979-V from Santa Cruz Biotechnology
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ATP1B4 RNAi - H00023439-R01 from Novus Biologicals
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MISSION® esiRNA - EHU141281 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3686 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3686 from Sigma-Aldrich
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ATP1B4 siRNA (Human) - CRH8273 from Cohesion Biosciences
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ATP1B4 - MBS828605 from MyBioSource
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shRNA set against Human ATP1B4 (NM_012069.4) - SHH242590 from Creative biogene
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Human ATP1B4 siRNA - orb268775 from Biorbyt
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ATP1B4 shRNA Plasmid (Human) - CHH8273 from Cohesion Biosciences
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ATP1B4 miRNA 3'UTR clone - MiUTR4H-TG10641 from Creative biogene
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