Gene Symbol |
TPSD1
|
Entrez Gene |
23430
|
Alt Symbol |
MCP7-LIKE, MCP7L1, MMCP-7L
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
tryptase delta 1
|
Other Description |
delta-tryptase|hmMCP-3-like tryptase III|mMCP-7-like delta II tryptase|mMCP-7-like-1|mMCP-7-like-2|mast cell tryptase|tryptase delta|tryptase-3
|
Swissprots |
O95824 Q96RZ5 Q9H2Y6 Q8TDI6 Q9UQI8 Q96L36 Q9BZJ3
|
Accessions |
AAD17845 AAD17861 AAK12909 AAK61272 EAW85680 EAW85681 Q9BZJ3 AF206664 AAG35694 AF421357 AAL86695 AY055427 AAL17874 BC069143 AAH69143 NM_012217 NP_036349
|
Function |
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. {ECO:0000250}.
|
Subcellular Location |
Secreted {ECO:0000250}. Note=Released from the secretory granules upon mast cell activation. {ECO:0000250}.
|
Tissue Specificity |
Expressed in colon, lung, heart and synovial tissue. May be specific to mast cells. {ECO:0000269|PubMed:12391231}.
|