Gene Symbol | TPSD1 |
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Entrez Gene | 23430 |
Alt Symbol | MCP7-LIKE, MCP7L1, MMCP-7L |
Species | Human |
Gene Type | protein-coding |
Description | tryptase delta 1 |
Other Description | delta-tryptase|hmMCP-3-like tryptase III|mMCP-7-like delta II tryptase|mMCP-7-like-1|mMCP-7-like-2|mast cell tryptase|tryptase delta|tryptase-3 |
Swissprots | O95824 Q96RZ5 Q9H2Y6 Q8TDI6 Q9UQI8 Q96L36 Q9BZJ3 |
Accessions | AAD17845 AAD17861 AAK12909 AAK61272 EAW85680 EAW85681 Q9BZJ3 AF206664 AAG35694 AF421357 AAL86695 AY055427 AAL17874 BC069143 AAH69143 NM_012217 NP_036349 |
Function | Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. Note=Released from the secretory granules upon mast cell activation. {ECO:0000250}. |
Tissue Specificity | Expressed in colon, lung, heart and synovial tissue. May be specific to mast cells. {ECO:0000269|PubMed:12391231}. |
TPSD1 CRISPR/Cas9 KO Plasmid (h) - sc-411739 from Santa Cruz Biotechnology
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TPSD1 HDR Plasmid (h) - sc-411739-HDR from Santa Cruz Biotechnology
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TPSD1 Double Nickase Plasmid (h) - sc-411739-NIC from Santa Cruz Biotechnology
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TPSD1 Double Nickase Plasmid (h2) - sc-411739-NIC-2 from Santa Cruz Biotechnology
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TPSD1 CRISPR Activation Plasmid (h) - sc-411739-ACT from Santa Cruz Biotechnology
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TPSD1 CRISPR Activation Plasmid (h2) - sc-411739-ACT-2 from Santa Cruz Biotechnology
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TPSD1 Lentiviral Activation Particles (h) - sc-411739-LAC from Santa Cruz Biotechnology
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TPSD1 Lentiviral Activation Particles (h2) - sc-411739-LAC-2 from Santa Cruz Biotechnology
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TPSD1 siRNA (h) - sc-106631 from Santa Cruz Biotechnology
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TPSD1 shRNA Plasmid (h) - sc-106631-SH from Santa Cruz Biotechnology
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TPSD1 shRNA (h) Lentiviral Particles - sc-106631-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU127461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21888 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21888 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00099 from Sigma-Aldrich
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TPSD1 siRNA (Human) - CRH8265 from Cohesion Biosciences
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TPSD1 - MBS8209036 from MyBioSource
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shRNA set against Human TPSD1 (NM_012217.2) - SHH433544 from Creative biogene
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TPSD1 shRNA Plasmid (Human) - CHH8265 from Cohesion Biosciences
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TPSD1 miRNA 3'UTR clone - MiUTR1H-10683 from Creative biogene
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