PFKFB2

Gene Symbol PFKFB2
Entrez Gene 5208
Alt Symbol PFK-2/FBPase-2
Species Human
Gene Type protein-coding
Description 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Other Description 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2|6PF-2-K/Fru-2,6-P2ASE heart-type isozyme|6PF-2-K/Fru-2,6-P2ase 2|PFK/FBPase 2|PFKFB, cardiac|fructose-2,6-bisphosphatase, cardiac isozyme
Swissprots O60825 O60824 Q5VVQ3 Q5VVQ4 Q9H3P1
Accessions CAA06605 EAW93507 EAW93508 O60825 AB044805 BAB19681 AF470623 AAL99386 AJ005578 CAA06606 AK125661 AK292883 BAF85572 AK295367 BAG58328 AK302315 BAG63653 BC069350 AAH69350 BC069385 AAH69385 BC069583 AAH69583 BC069586 AAH69586 BC069600 AAH69600 BC075075 AAH75075 BC075076 AAH75076 BC112103 AAI12104 BC112105 AAI12106 BX510096 CR749442 CAH18280 EU334168 ABY59650 XM_005273162 XP_005273219 XM_006711381 XP_006711444 XM_011509625 XP_011507927 XM_011509626 XP_011507928 XM_011509627 XP_011507929 XM_011509628 XP_011507930 NM_001018053 NP_001018063 NM_006212 NP_006203
Function Synthesis and degradation of fructose 2,6-bisphosphate.
Tissue Specificity Heart.
Top Pathways AMPK signaling pathway, Fructose and mannose metabolism

PFKFB2 (D5I5F) Rabbit mAb - 13029 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D5I5F
Western blot analysis of extracts from LNCaP, Hep G2, and MCF7 cells using PFKFB2 (D5I5F) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).

PFKFB2 (D7G5R) Rabbit mAb - 13045 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D7G5R
Western blot analysis of extracts from LNCaP, Hep G2, and MCF7 cells using PFKFB2 (D7G5R) Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).

Phospho-PFKFB2 (Ser483) (D4R1W) Rabbit mAb - 13064 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D4R1W
Western blot analysis of extracts from serum starved HeLa cells, untreated (-) or treated with insulin (150 nM, 5 min; +) or IGF-1 (100 ng/ml, 5 min; +), using Phospho-PFKFB2 (Ser483) (D4R1W) Rabbit mAb (upper) or PFKFB2 (D7G5R) Rabbit mAb #13045 (lower). The phospho-specificity of Phospho-PFKFB2 (Ser483) (D4R1W) Rabbit mAb is verified by treating the nitrocellulose membranes with calf intestinal alkaline phosphatase (CIP) and λ protein phosphatase (λ PP) following transfer of proteins from the SDS-PAGE gel to the membranes.

Phospho-PFK-2 (Ser466) Antibody - 4081 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

PFK-2 car (D-1) - sc-377416 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PFK-2 car (D-1): sc-377416. Western blot analysis of PFK-2 car expression in non-transfected: sc-117752 (A) and mouse PFK-2 car transfected: sc-122507 (B) 293T whole cell lysates.

PFK-2 car (N-20) - sc-50953 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PFK-2 car (P-17) - sc-50954 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PFK-2 car (P-17): sc-50954. Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart muscle tissue showing cytoplasmic staining of myocytes.

PFK-2 car (Y-13) - sc-50956 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PFK-2 car (Y-13): sc-50956. Western blot analysis of PFK-2 car expression in non-transfected: sc-117752 (A) and mouse PFK-2 car transfected: sc-122507 (B) 293T whole cell lysates.

p-PFK-2 car (B-3) - sc-373806 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of PFK-2 car phosphorylation in non-transfected: sc-117752 (A,D), untreated mouse PFK-2 car transfected: sc-122507 (B,E) and lambda protein phosphatase (sc-200312A) treated mouse PFK-2 car transfected: sc-122507 (C,F) 293T whole cell lysates. Antibodies tested include p-PFK-2 car (B-3): sc-373806 (A,B,C) and PFK-2 car (Y-13): sc-50956 (D,E,F).

p-PFK-2 car (Ser 466) - sc-32966 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
p-PFK-2 car (Ser 466): sc-32966. Western blot analysis of p-PFK-2 car phosphorylation in non-transfected: sc-117752 (A) and mouse p-PFK-2 car transfected: sc-122507 (B) 293T whole cell lysates.

p-PFK-2 car (Ser 483) - sc-32967 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
p-PFK-2 car (Ser 483): sc-32967. Western blot analysis of p-PFK-2 car phosphorylation in non-transfected: sc-117752 (A) and mouse p-PFK-2 car transfected: sc-122507 (B) 293T whole cell lysates.

Anti-PFKFB2 Antibody (aa451-500) - LS-C117788 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PFKFB2 Antibody (N-Terminus, AP) - LS-C245275 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKFB2 Antibody (C-Terminus) - LS-C135390 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PFKFB2 antibody LS-C135390 Western blot of Mouse Liver lysate. Antibody concentration 1 ug/ml.

Anti-PFKFB2 Antibody (aa336-385) - LS-C135389 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PFKFB2 antibody LS-C135389 Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.

Anti-PFKFB2 Antibody (N-Terminus, APC) - LS-C245276 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKFB2 Antibody (N-Terminus, FITC) - LS-C245278 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKFB2 Antibody (N-Terminus, Biotin) - LS-C245277 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKFB2 Antibody (N-Terminus, PE) - LS-C245279 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKFB2 Antibody (N-Terminus, Azide-free, HRP) - LS-C247751 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKFB2 Antibody (phospho-Ser483) - LS-C313622 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PFKFB2 Antibody (Pro479) - LS-C176450 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of PFKFB2 (P479) pAb in paraffin-embedded human colon carcinoma tissue.

Anti-PFKFB2 Antibody (N-Terminus) - LS-C328197 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKFB2 Antibody (aa1-50) - LS-C118702 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from Jurkat cells, using PFKFB2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-PFKFB2 Antibody (phospho-Ser483) - LS-C199436 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human colon carcinoma, using PFKFB2 (Phospho-Ser483) Antibody. The sample on the right was incubated with synthetic peptide.
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