Gene Symbol | PFKFB2 |
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Entrez Gene | 5208 |
Alt Symbol | PFK-2/FBPase-2 |
Species | Human |
Gene Type | protein-coding |
Description | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
Other Description | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2|6PF-2-K/Fru-2,6-P2ASE heart-type isozyme|6PF-2-K/Fru-2,6-P2ase 2|PFK/FBPase 2|PFKFB, cardiac|fructose-2,6-bisphosphatase, cardiac isozyme |
Swissprots | O60825 O60824 Q5VVQ3 Q5VVQ4 Q9H3P1 |
Accessions | CAA06605 EAW93507 EAW93508 O60825 AB044805 BAB19681 AF470623 AAL99386 AJ005578 CAA06606 AK125661 AK292883 BAF85572 AK295367 BAG58328 AK302315 BAG63653 BC069350 AAH69350 BC069385 AAH69385 BC069583 AAH69583 BC069586 AAH69586 BC069600 AAH69600 BC075075 AAH75075 BC075076 AAH75076 BC112103 AAI12104 BC112105 AAI12106 BX510096 CR749442 CAH18280 EU334168 ABY59650 XM_005273162 XP_005273219 XM_006711381 XP_006711444 XM_011509625 XP_011507927 XM_011509626 XP_011507928 XM_011509627 XP_011507929 XM_011509628 XP_011507930 NM_001018053 NP_001018063 NM_006212 NP_006203 |
Function | Synthesis and degradation of fructose 2,6-bisphosphate. |
Tissue Specificity | Heart. |
Top Pathways | AMPK signaling pathway, Fructose and mannose metabolism |
PFK-2 car CRISPR/Cas9 KO Plasmid (h) - sc-401358 from Santa Cruz Biotechnology
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PFK-2 car HDR Plasmid (h) - sc-401358-HDR from Santa Cruz Biotechnology
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PFK-2 car Double Nickase Plasmid (h) - sc-401358-NIC from Santa Cruz Biotechnology
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PFK-2 car Double Nickase Plasmid (h2) - sc-401358-NIC-2 from Santa Cruz Biotechnology
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PFK-2 car CRISPR Activation Plasmid (h) - sc-401358-ACT from Santa Cruz Biotechnology
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PFK-2 car CRISPR Activation Plasmid (h2) - sc-401358-ACT-2 from Santa Cruz Biotechnology
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PFK-2 car Lentiviral Activation Particles (h) - sc-401358-LAC from Santa Cruz Biotechnology
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PFK-2 car Lentiviral Activation Particles (h2) - sc-401358-LAC-2 from Santa Cruz Biotechnology
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PFK-2 car siRNA (h) - sc-44675 from Santa Cruz Biotechnology
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PFK-2 car shRNA Plasmid (h) - sc-44675-SH from Santa Cruz Biotechnology
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PFK-2 car shRNA (h) Lentiviral Particles - sc-44675-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU079771 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0394 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0396 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0395 from Sigma-Aldrich
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MISSION® siRNA - SIHK1577 from Sigma-Aldrich
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MISSION® siRNA - SIHK1578 from Sigma-Aldrich
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MISSION® siRNA - SIHK1579 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16655 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16655 from Sigma-Aldrich
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PFKFB2 siRNA (Human) - CRH3478 from Cohesion Biosciences
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PFKFB2 RNAi - H00005208-R06 from Novus Biologicals
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PFKFB2 RNAi - H00005208-R05 from Novus Biologicals
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shRNA set against Human PFKFB2 (NM_006212.2) - SHH373920 from Creative biogene
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shRNA set against Human PFKFB2(NM_001018053.1) - SHR107556 from Creative biogene
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