| Gene Symbol |
DYNLRB2
|
| Entrez Gene |
83657
|
| Alt Symbol |
DNCL2B, DNLC2B, ROBLD2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dynein, light chain, roadblock-type 2
|
| Other Description |
bithoraxoid-like protein|dynein light chain 2B, cytoplasmic|dynein light chain roadblock-type 2|dynein, cytoplasmic, light polypeptide 2B|roadblock domain-containing protein 2
|
| Swissprots |
Q8TF09
|
| Accessions |
EAW95568 Q8TF09 AF125108 AAL75945 BC035232 BC054892 AAH54892 CD676360 DB458006 HY018370 HY123054 HY201608 XM_005256188 XP_005256245 XM_006721295 XP_006721358 XM_006721296 XP_006721359 XM_011523370 XP_011521672 NM_001305017 NP_001291946 NM_130897 NP_570967 NR_130942 NR_130943
|
| Function |
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
|
| Subcellular Location |
Cytoplasm, cytoskeleton.
|
| Tissue Specificity |
High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte.
|
![Western Blot: DYNLRB2 Overexpression Lysate (Adult Normal) [NBP2-05721] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DYNLRB2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10462_DYNLRB2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05721-img0001.jpg)