Gene Symbol | DYNLRB2 |
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Entrez Gene | 83657 |
Alt Symbol | DNCL2B, DNLC2B, ROBLD2 |
Species | Human |
Gene Type | protein-coding |
Description | dynein, light chain, roadblock-type 2 |
Other Description | bithoraxoid-like protein|dynein light chain 2B, cytoplasmic|dynein light chain roadblock-type 2|dynein, cytoplasmic, light polypeptide 2B|roadblock domain-containing protein 2 |
Swissprots | Q8TF09 |
Accessions | EAW95568 Q8TF09 AF125108 AAL75945 BC035232 BC054892 AAH54892 CD676360 DB458006 HY018370 HY123054 HY201608 XM_005256188 XP_005256245 XM_006721295 XP_006721358 XM_006721296 XP_006721359 XM_011523370 XP_011521672 NM_001305017 NP_001291946 NM_130897 NP_570967 NR_130942 NR_130943 |
Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. |
Subcellular Location | Cytoplasm, cytoskeleton. |
Tissue Specificity | High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte. |
DNLC2B CRISPR/Cas9 KO Plasmid (h) - sc-413489 from Santa Cruz Biotechnology
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DNLC2B HDR Plasmid (h) - sc-413489-HDR from Santa Cruz Biotechnology
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DNLC2B Double Nickase Plasmid (h) - sc-413489-NIC from Santa Cruz Biotechnology
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DNLC2B Double Nickase Plasmid (h2) - sc-413489-NIC-2 from Santa Cruz Biotechnology
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DNLC2B CRISPR Activation Plasmid (h) - sc-413489-ACT from Santa Cruz Biotechnology
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DNLC2B CRISPR Activation Plasmid (h2) - sc-413489-ACT-2 from Santa Cruz Biotechnology
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DNLC2B Lentiviral Activation Particles (h) - sc-413489-LAC from Santa Cruz Biotechnology
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DNLC2B Lentiviral Activation Particles (h2) - sc-413489-LAC-2 from Santa Cruz Biotechnology
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DNLC2B siRNA (h) - sc-93148 from Santa Cruz Biotechnology
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DNLC2B shRNA Plasmid (h) - sc-93148-SH from Santa Cruz Biotechnology
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DNLC2B shRNA (h) Lentiviral Particles - sc-93148-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN7591 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7591 from Sigma-Aldrich
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DYNLRB2 siRNA (Human) - CRJ3155 from Cohesion Biosciences
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DYNLRB2 - MBS8239894 from MyBioSource
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shRNA set against Human DYNLRB2 (NM_130897.1) - SHH282213 from Creative biogene
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shRNA set against Human DYNLRB2(NM_130897.1) - SHH020567 from Creative biogene
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Human DYNLRB2 siRNA - orb273656 from Biorbyt
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DYNLRB2 shRNA Plasmid (Human) - CHJ3155 from Cohesion Biosciences
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DYNLRB2 miRNA 3'UTR clone - MiUTR1H-03058 from Creative biogene
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