C1orf86

Gene Symbol C1orf86
Entrez Gene 199990
Alt Symbol FAAP20, FP7162
Species Human
Gene Type protein-coding
Description chromosome 1 open reading frame 86
Other Description Fanconi anemia-associated protein of 20 kDa
Swissprots F2Z2L4 A6PW40 Q6NZ36 Q96ND7 A8MQT6 Q6ZT64 Q71M24 A6PW39 A6PW41
Accessions EAW56125 EAW56126 EAW56127 EAW56128 EAW56129 Q6NZ36 AF461903 AAQ04817 AF469129 AAP97719 AK054818 AK055593 BAB70965 AK093927 BAC04254 AK125445 AK126870 BAC86730 AK127994 BAC87220 AK128507 AL545931 BC041041 BC066360 AAH66360 BC078145 BC103992 AAI03993 BG825658 BM127377 BM674927 BM682341 BU192678 BU542153 BU626113 CN397640 DA596011 XM_006710419 XP_006710482 XM_006710420 XP_006710483 XM_006710421 XP_006710484 XM_011540914 XP_011539216 XM_011540915 XP_011539217 XM_011540916 XP_011539218 XM_011540917 XP_011539219 XM_011540918 XP_011539220 XM_011540919 XP_011539221 XM_011540920 XP_011539222 XM_011540921 XP_011539223 XM_011540922 XP_011539224 NR_024445 NM_001146310 NP_001139782 NM_001256945 NP_001243874 NM_001256946 NP_001243875 NM_001256947 NP_001243876 NM_001282670 NP_001269599 NM_001282671 NP_001269600 NM_001282672 NP_001269601 NM_001282673 NP_001269602 NM_182533 NP_872339 NR_046427
Function Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1. {ECO:0000269|PubMed:22266823, ECO:0000269|PubMed:22343915, ECO:0000269|PubMed:22396592, ECO:0000269|PubMed:22705371}.
Subcellular Location Nucleus. Chromosome. Note=Following DNA damage, recruited to DNA interstrand cross-links (ICLs) sites by binding to ubiquitin generated by RNF8.

C1orf86 CRISPR/Cas9 KO Plasmid (h) - sc-410649 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1orf86 HDR Plasmid (h) - sc-410649-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1orf86 Double Nickase Plasmid (h) - sc-410649-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1orf86 Double Nickase Plasmid (h2) - sc-410649-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1orf86 CRISPR Activation Plasmid (h) - sc-410649-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1orf86 CRISPR Activation Plasmid (h2) - sc-410649-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1orf86 Lentiviral Activation Particles (h) - sc-410649-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C1orf86 Lentiviral Activation Particles (h2) - sc-410649-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MISSION® esiRNA - EHU128111 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4670 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4670 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00060 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00060

FAAP20 siRNA (Human) - CRJ6228 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FAAP20 - MBS8235083 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C1orf86 (NM_182533.2) - SHH250633 from Creative biogene

Category siRNA
Species Reactivities Human

Human FAAP20 siRNA - orb276729 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FAAP20 shRNA Plasmid (Human) - CHJ6228 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

C1ORF86 miRNA 3'UTR clone - MiUTR1H-01277 from Creative biogene

Species Reactivities Human
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