Gene Symbol | PPIL1 |
---|---|
Entrez Gene | 51645 |
Alt Symbol | CGI-124, CYPL1, PPIase, hCyPX |
Species | Human |
Gene Type | protein-coding |
Description | peptidylprolyl isomerase (cyclophilin)-like 1 |
Other Description | cyclophilin-related gene 1|peptidyl-prolyl cis-trans isomerase|peptidyl-prolyl cis-trans isomerase-like 1|rotamase PPIL1 |
Swissprots | O15001 Q9Y3C6 Q5TDC9 |
Accessions | CAF32598 EAX03916 EAX03917 EAX03918 Q9Y3C6 AF151882 AAD34119 AK026636 AY359032 AAQ89391 BC003048 AAH03048 BU195579 DQ892513 ABM83439 DQ895727 ABM86653 NM_016059 NP_057143 |
Function | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing. {ECO:0000269|PubMed:16595688}. |
Tissue Specificity | Ubiquitous, with the most abundant expression in heart and skeletal muscle. |
Top Pathways | Spliceosome |