Gene Symbol | PPIL1 |
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Entrez Gene | 51645 |
Alt Symbol | CGI-124, CYPL1, PPIase, hCyPX |
Species | Human |
Gene Type | protein-coding |
Description | peptidylprolyl isomerase (cyclophilin)-like 1 |
Other Description | cyclophilin-related gene 1|peptidyl-prolyl cis-trans isomerase|peptidyl-prolyl cis-trans isomerase-like 1|rotamase PPIL1 |
Swissprots | O15001 Q9Y3C6 Q5TDC9 |
Accessions | CAF32598 EAX03916 EAX03917 EAX03918 Q9Y3C6 AF151882 AAD34119 AK026636 AY359032 AAQ89391 BC003048 AAH03048 BU195579 DQ892513 ABM83439 DQ895727 ABM86653 NM_016059 NP_057143 |
Function | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing. {ECO:0000269|PubMed:16595688}. |
Tissue Specificity | Ubiquitous, with the most abundant expression in heart and skeletal muscle. |
Top Pathways | Spliceosome |
PPIL1 CRISPR/Cas9 KO Plasmid (h) - sc-412231 from Santa Cruz Biotechnology
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PPIL1 HDR Plasmid (h) - sc-412231-HDR from Santa Cruz Biotechnology
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PPIL1 Double Nickase Plasmid (h) - sc-412231-NIC from Santa Cruz Biotechnology
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PPIL1 Double Nickase Plasmid (h2) - sc-412231-NIC-2 from Santa Cruz Biotechnology
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PPIL1 CRISPR Activation Plasmid (h) - sc-412231-ACT from Santa Cruz Biotechnology
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PPIL1 CRISPR Activation Plasmid (h2) - sc-412231-ACT-2 from Santa Cruz Biotechnology
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PPIL1 Lentiviral Activation Particles (h) - sc-412231-LAC from Santa Cruz Biotechnology
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PPIL1 Lentiviral Activation Particles (h2) - sc-412231-LAC-2 from Santa Cruz Biotechnology
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PPIL1 siRNA (h) - sc-95262 from Santa Cruz Biotechnology
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PPIL1 shRNA Plasmid (h) - sc-95262-SH from Santa Cruz Biotechnology
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PPIL1 shRNA (h) Lentiviral Particles - sc-95262-V from Santa Cruz Biotechnology
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PPIL1 RNAi - H00051645-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN17231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17231 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07505 from Sigma-Aldrich
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PPIL1 siRNA (Human) - CRH9876 from Cohesion Biosciences
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shRNA set against Human PPIL1 (NM_016059.4) - SHH380692 from Creative biogene
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Human PPIL1 siRNA - orb270378 from Biorbyt
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PPIL1 shRNA Plasmid (Human) - CHH9876 from Cohesion Biosciences
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PPIL1 miRNA 3'UTR clone - MiUTR3H-04048 from Creative biogene
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