Gene Symbol | ADGRB1 |
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Entrez Gene | 575 |
Alt Symbol | BAI1, GDAIF |
Species | Human |
Gene Type | protein-coding |
Description | adhesion G protein-coupled receptor B1 |
Other Description | brain-specific angiogenesis inhibitor 1 |
Swissprots | O14514 |
Accessions | EAW82323 O14514 AB005297 BAA23647 AK123982 BC156200 AAI56201 XM_011517199 XP_011515501 XM_011517200 XP_011515502 XM_011517201 XP_011515503 XM_011517202 XP_011515504 XR_928342 NM_001702 NP_001693 |
Function | Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain. {ECO:0000269|PubMed:11875720}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:12074842}; Multi-pass membrane protein {ECO:0000269|PubMed:12074842}. Note=Likely to be concentrated at cell-cell adhesion sites. |
Tissue Specificity | Specifically expressed in brain. Reduced or no expression is observed in some glioblastoma cell lines and cancer tissues. No expression in astrocytes. {ECO:0000269|PubMed:11875720, ECO:0000269|PubMed:12074842, ECO:0000269|PubMed:12507886}. |
Top Pathways | p53 signaling pathway |
ADGRB1 / BAI1 Antibody Blocking Peptide - LS-E29171 from LifeSpan Bioscience
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ADGRB1 / BAI1 Antibody Blocking Peptide - LS-E29803 from LifeSpan Bioscience
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ADGRB1 / BAI1 Antibody Blocking Peptide - LS-E29804 from LifeSpan Bioscience
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ADGRB1 / BAI1 Antibody Blocking Peptide - LS-E29809 from LifeSpan Bioscience
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BAI1 Blocking Peptide - NB110-81586PEP from Novus Biologicals
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Recombinant Human BAI1, CF - 4969-BA-050 from R&D Systems
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Recombinant Human BAI1 Protein, His-tagged - BAI1-921H from Creative Biomart
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Recombinant Brain Specific Angiogenesis Inhibitor 1 (BAI1) - RPC346Hu01 from Uscn Life Science Inc.
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BAI-1 (Q732) Peptide - BS2784P from Bioworld Technology
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Recombinant Human BAI1 Protein, CF - 4969-BA from R&D Systems
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BAI1 Blocking Peptide - abx161790 from Abbexa
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BAI1-Antibody-C-term-Blocking-Peptide - BP8170a from Abgent, a WuXi AppTec company
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BAI1 Peptide, Human - M34GP01309H from Creative Peptides
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BAI1 Blocking Peptide - CBP4579 from Cohesion Biosciences
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BAI1 Blocking Peptide - orb392924 from Biorbyt
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Brain-specific angiogenesis inhibitor 1 (BAI1), partial, Recombinant Protein - MBS1165408 from MyBioSource
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Recombinant Human BAI1 Protein, CF - 4969-BA from Novus Biologicals
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