ADGRB1

Gene Symbol ADGRB1
Entrez Gene 575
Alt Symbol BAI1, GDAIF
Species Human
Gene Type protein-coding
Description adhesion G protein-coupled receptor B1
Other Description brain-specific angiogenesis inhibitor 1
Swissprots O14514
Accessions EAW82323 O14514 AB005297 BAA23647 AK123982 BC156200 AAI56201 XM_011517199 XP_011515501 XM_011517200 XP_011515502 XM_011517201 XP_011515503 XM_011517202 XP_011515504 XR_928342 NM_001702 NP_001693
Function Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Likely to be a potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53 signal in suppression of glioblastoma. May function in cell adhesion and signal transduction in the brain. {ECO:0000269|PubMed:11875720}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:12074842}; Multi-pass membrane protein {ECO:0000269|PubMed:12074842}. Note=Likely to be concentrated at cell-cell adhesion sites.
Tissue Specificity Specifically expressed in brain. Reduced or no expression is observed in some glioblastoma cell lines and cancer tissues. No expression in astrocytes. {ECO:0000269|PubMed:11875720, ECO:0000269|PubMed:12074842, ECO:0000269|PubMed:12507886}.
Top Pathways p53 signaling pathway

BAI-1 CRISPR/Cas9 KO Plasmid (h) - sc-406202 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAI-1 HDR Plasmid (h) - sc-406202-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAI-1 Double Nickase Plasmid (h) - sc-406202-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAI-1 Double Nickase Plasmid (h2) - sc-406202-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAI-1 CRISPR Activation Plasmid (h) - sc-406202-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAI-1 CRISPR Activation Plasmid (h2) - sc-406202-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAI-1 Lentiviral Activation Particles (h) - sc-406202-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAI-1 Lentiviral Activation Particles (h2) - sc-406202-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BAI-1 siRNA (h) - sc-45208 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BAI-1 shRNA Plasmid (h) - sc-45208-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BAI-1 shRNA (h) Lentiviral Particles - sc-45208-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BAI1 RNAi - H00000575-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU030041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3848 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3848 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04214 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04214

BAI1 siRNA (Human) - CRH0393 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BAI1 - MBS8219870 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BAI1 (NM_001702.2) - SHH244714 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human BAI1(NM_001702.2) - SHG090739 from Creative biogene

Category siRNA
Species Reactivities Human

Human BAI1 siRNA - orb260895 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BAI1 shRNA Plasmid (Human) - CHH0393 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BAI1 miRNA 3'UTR clone - MiUTR1H-00795 from Creative biogene

Species Reactivities Human
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