| Gene Symbol |
AHCYL1
|
| Entrez Gene |
10768
|
| Alt Symbol |
DCAL, IRBIT, PPP1R78, PRO0233, XPVKONA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adenosylhomocysteinase-like 1
|
| Other Description |
DC-expressed AHCY-like molecule|IP(3)Rs binding protein released with IP(3)|S-adenosyl homocysteine hydrolase homolog|S-adenosyl-L-homocysteine hydrolase 2|S-adenosylhomocysteine hydrolase-like protein 1|adoHcyase 2|dendritic cell expressed AHCY-like protein|inositol 1,4,5-trisphosphate receptor-binding protein|protein phosphatase 1, regulatory subunit 78|putative adenosylhomocysteinase 2
|
| Swissprots |
Q2TAJ6 Q5VSM0 Q502W8 B4E168 Q9UG84 Q6P171 Q96PK4 O43865
|
| Accessions |
CAH70965 CAH70966 CAV30704 EAW56422 EAW56423 EAW56424 EAW56425 EAW56426 EAW56427 O43865 AA427939 AA865152 AF035319 AAB88189 AF090905 AAF24028 AF315687 AAL26869 AK131563 BAD18696 AK303690 BAG64680 AK308080 AK313392 BAG36190 AK316110 BAH14481 AL049954 CAB43223 BC003631 AAH03631 BC007576 AAH07576 BC010681 AAH10681 BC016942 AAH16942 BC065254 AAH65254 BC095476 AAH95476 BC110896 AAI10897 BC111563 AAI11564 BC140414 AAI40415 BC146492 AAI46493 BK005417 DAA05762 BK005418 DAA05763 BQ774807 CF456195 DC328766 DC329490 DQ891021 ABM81947 DQ894201 ABM85127 EU831760 ACE87278 EU831838 ACE86597 U82761 AAC01960 XM_011540535 XP_011538837 XR_946527 NM_001242673 NP_001229602 NM_001242674 NP_001229603 NM_001242675 NP_001229604 NM_001242676 NP_001229605 NM_006621 NP_006612
|
| Function |
Acts as a (dATP)-dependent inhibitor of ribonucleotide reductase large subunit RRM1, controlling the endogenous dNTP pool and ensuring normal cell cycle progression. {ECO:0000269|PubMed:25237103}.
|
| Subcellular Location |
Endoplasmic reticulum {ECO:0000250}.
|
| Tissue Specificity |
Expressed in dendritic cells. {ECO:0000269|PubMed:11904675}.
|
| Top Pathways |
Cysteine and methionine metabolism
|
![Western Blot: AHCYL1 Overexpression Lysate [L009T6] - Lane 1: AHCYL1 transfected lysate (69 KDa). Lane 2: Non-transfected lysate.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/26273_AHCYL1%2520Overexpression%2520Lysate-Western%2520Blot-L009T6-img0002.jpg)