Gene Symbol | ROBO3 |
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Entrez Gene | 64221 |
Alt Symbol | HGPPS, HGPS, RBIG1, RIG1 |
Species | Human |
Gene Type | protein-coding |
Description | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
Other Description | retinoblastoma inhibiting gene 1|roundabout homolog 3|roundabout-like protein 3 |
Swissprots | Q96MS0 |
Accessions | EAW67602 EAW67603 EAW67604 EAW67605 EAW67606 EAW67607 EAW67608 EAW67609 Q96MS0 AK024697 BAB14966 AK225076 AK291045 BAF83734 AK295475 BAG58402 AK298792 BAG60929 AY509035 AAS91662 BC008623 AAH08623 BC086878 BC113744 BC148593 AAI48594 N80769 XM_011542953 XP_011541255 NM_022370 NP_071765 |
Function | Thought to be involved during neural development in axonal navigation at the ventral midline of the neural tube. In spinal chord development plays a role in guiding commissural axons probably by preventing premature sensitivity to Slit proteins thus inhibiting Slit signaling through ROBO1 (By similarity). Required for hindbrain axon midline crossing. {ECO:0000250, ECO:0000269|PubMed:15105459}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Top Pathways | Axon guidance |
Human Robo3 full length protein - ab132280 from Abcam
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Mouse Robo3 peptide - ab30862 from Abcam
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ROBO3 Antibody Blocking Peptide - LS-E26336 from LifeSpan Bioscience
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ROBO3 Antibody Blocking Peptide - LS-E26337 from LifeSpan Bioscience
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ROBO3 Antibody Blocking Peptide - LS-E26007 from LifeSpan Bioscience
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ROBO3 Recombinant Protein - H00064221-P01 from Novus Biologicals
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Robo3 (internal) blocking peptide - GTX89080-PEP from GeneTex
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Recombinant Human ROBO3 Fc Chimera, CF - 3076-RB-050 from R&D Systems
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ROBO3 Peptide - AC21-0835-P from Abcore
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ROBO3 Peptide - AC21-1171-P from Abcore
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ROBO3 - H00064221-P01-10 from Acris Antibodies
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ROBO3 - H00064221-P01-25 from Acris Antibodies
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Robo3 Peptide - 46-318P from ProSci
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ROBO3 Peptide - 42-734P from ProSci
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ROBO3 fusion protein - ag13530 from Proteintech Group
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ROBO3 fusion protein - ag2608 from Proteintech Group
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Recombinant Human ROBO3 - ROBO3-896H from Creative Biomart
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Recombinant Human Roundabout homolog 3(ROBO3) ,partial - CSB-YP846671HU CSB-EP846671HU CSB-BP846671HU CSB-MP846671HU from Cusabio
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Recombinant Human ROBO3 Fc Chimera Protein, CF - 3076-RB from R&D Systems
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ROBO3, Peptide - MBS428166 from MyBioSource
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ROBO3/RIG1, Peptide - MBS425619 from MyBioSource
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ROBO3 Recombinant Protein Antigen - NBP1-83626PEP from Novus Biologicals
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ROBO3 Peptide, Human - M34GP13459H from Creative Peptides
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Robo3 Immunizing peptide - orb50278 from Biorbyt
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ROBO3 Immunizing peptide - orb15935 from Biorbyt
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