| Gene Symbol |
ROMO1
|
| Entrez Gene |
140823
|
| Alt Symbol |
C20orf52, MTGM, MTGMP, bA353C18.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
reactive oxygen species modulator 1
|
| Other Description |
PCM19|ROS modulator 1|epididymis tissue protein Li 175|glyrichin|mitochondrial targeting GXXXG protein|mitochondrial targeting GxxxG motif protein|protein MGR2 homolog
|
| Swissprots |
A7M872 Q3MHD5 Q5QP16 E1P5R9 E9KL28 P60602
|
| Accessions |
EAW76168 EAW76169 P60602 AK000548 AM397244 CAL37002 AM397245 CAL37003 AM397246 CAL37004 BC008488 AAH08488 BC105281 AAI05282 BM353595 GU727625 ADU87627 JF432445 ADZ15662 NM_080748 NP_542786
|
| Function |
Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:16842742, ECO:0000269|PubMed:19535734}; Single-pass membrane protein {ECO:0000269|PubMed:16842742, ECO:0000269|PubMed:19535734}.
|
| Tissue Specificity |
Up-regulated in a number of cancer cell lines when compared to a normal lung fibroblast cell line. Highly expressed in brain tumors. {ECO:0000269|PubMed:16842742, ECO:0000269|PubMed:19535734}.
|