| Gene Symbol |
BRPF1
|
| Entrez Gene |
7862
|
| Alt Symbol |
BR140
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
bromodomain and PHD finger containing, 1
|
| Other Description |
bromodomain and PHD finger-containing protein 1|bromodomain-containing protein, 140kD|peregrin
|
| Swissprots |
Q8TCM6 B4DEZ6 Q9UHI0 Q7Z6E0 P55201
|
| Accessions |
AAF19605 EAW63972 EAW63973 EAW63974 EAW63975 EAW63976 P55201 AI356310 AK293865 BAG57257 AL713696 CAD28495 BC036374 BC053851 AAH53851 BC068262 BG704575 M91585 AAB02119 XM_005265449 XP_005265506 XM_005265450 XP_005265507 XM_005265451 XP_005265508 XM_005265452 XP_005265509 XM_005265453 XP_005265510 XM_005265454 XP_005265511 XM_011534101 XP_011532403 XM_011534102 XP_011532404 NM_001003694 NP_001003694 NM_004634 NP_004625
|
| Function |
Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2. {ECO:0000269|PubMed:16387653, ECO:0000269|PubMed:18794358}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:18794358}. Cytoplasm {ECO:0000269|PubMed:18794358}. Note=Localization to the nucleus depends on KAT6A, ING5 and MEAF6.
|
| Tissue Specificity |
High levels in testis.
|