Gene Symbol | BRPF1 |
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Entrez Gene | 7862 |
Alt Symbol | BR140 |
Species | Human |
Gene Type | protein-coding |
Description | bromodomain and PHD finger containing, 1 |
Other Description | bromodomain and PHD finger-containing protein 1|bromodomain-containing protein, 140kD|peregrin |
Swissprots | Q8TCM6 B4DEZ6 Q9UHI0 Q7Z6E0 P55201 |
Accessions | AAF19605 EAW63972 EAW63973 EAW63974 EAW63975 EAW63976 P55201 AI356310 AK293865 BAG57257 AL713696 CAD28495 BC036374 BC053851 AAH53851 BC068262 BG704575 M91585 AAB02119 XM_005265449 XP_005265506 XM_005265450 XP_005265507 XM_005265451 XP_005265508 XM_005265452 XP_005265509 XM_005265453 XP_005265510 XM_005265454 XP_005265511 XM_011534101 XP_011532403 XM_011534102 XP_011532404 NM_001003694 NP_001003694 NM_004634 NP_004625 |
Function | Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2. {ECO:0000269|PubMed:16387653, ECO:0000269|PubMed:18794358}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:18794358}. Cytoplasm {ECO:0000269|PubMed:18794358}. Note=Localization to the nucleus depends on KAT6A, ING5 and MEAF6. |
Tissue Specificity | High levels in testis. |
Peregrin CRISPR/Cas9 KO Plasmid (h) - sc-409706 from Santa Cruz Biotechnology
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Peregrin HDR Plasmid (h) - sc-409706-HDR from Santa Cruz Biotechnology
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Peregrin Double Nickase Plasmid (h) - sc-409706-NIC from Santa Cruz Biotechnology
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Peregrin Double Nickase Plasmid (h2) - sc-409706-NIC-2 from Santa Cruz Biotechnology
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Peregrin CRISPR Activation Plasmid (h) - sc-409706-ACT from Santa Cruz Biotechnology
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Peregrin CRISPR Activation Plasmid (h2) - sc-409706-ACT-2 from Santa Cruz Biotechnology
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Peregrin Lentiviral Activation Particles (h) - sc-409706-LAC from Santa Cruz Biotechnology
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Peregrin Lentiviral Activation Particles (h2) - sc-409706-LAC-2 from Santa Cruz Biotechnology
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Peregrin siRNA (h) - sc-78127 from Santa Cruz Biotechnology
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Peregrin shRNA Plasmid (h) - sc-78127-SH from Santa Cruz Biotechnology
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Peregrin shRNA (h) Lentiviral Particles - sc-78127-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN4069 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4069 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05664 from Sigma-Aldrich
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BRPF1 siRNA (Human) - CRH5299 from Cohesion Biosciences
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BRPF1 RNAi - H00007862-R02 from Novus Biologicals
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BRPF1 - MBS8213651 from MyBioSource
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shRNA set against Human BRPF1 (NM_004634.2) - SHH247830 from Creative biogene
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shRNA set against Human BRPF1(NM_004634.2) - SHG105305 from Creative biogene
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shRNA set against Human BRPF1(NM_001003694.1) - SHG105361 from Creative biogene
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shRNA set against Human BRPF1(NM_004634.2) - SHG105397 from Creative biogene
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Human BRPF1 siRNA - orb265801 from Biorbyt
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BRPF1 shRNA Plasmid (Human) - CHH5299 from Cohesion Biosciences
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BRPF1 miRNA 3'UTR clone - MiUTR1H-00949 from Creative biogene
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BRPF1 miRNA 3'UTR clone - MiUTR1H-00950 from Creative biogene
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