| Gene Symbol |
MYH11
|
| Entrez Gene |
4629
|
| Alt Symbol |
AAT4, FAA4, SMHC, SMMHC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myosin, heavy chain 11, smooth muscle
|
| Other Description |
myosin heavy chain 11|myosin heavy chain, smooth muscle isoform|myosin, heavy polypeptide 11, smooth muscle|myosin-11
|
| Swissprots |
O00396 Q3MIV8 D2JYH7 Q3MNF0 Q3MNF1 P35749 O94944 P78422
|
| Accessions |
AAC31665 AAC35212 ACZ58373 ACZ58374 EAW53924 EAW53925 EAW53926 EAW53927 EAW53928 EAW53929 EAW53930 P35749 AA552189 AB020673 BAA74889 AF013570 AAB69326 AF020091 AAB69327 AK125033 AK308389 AK311080 AY520816 AAS98910 AY520817 AAS98911 BC031040 AAH31040 BC080545 AAH80545 BC101677 AAI01678 BC104906 AAI04907 BC143364 AAI43365 BX489788 BX641087 CR749516 CAH18331 D10667 BAA36971 EU489063 ACB05996 S67238 AAB28950 S67240 AAB28951 X69292 CAA49154 XM_011522502 XP_011520804 XM_011546698 XP_011545000 NM_001040113 NP_001035202 NM_001040114 NP_001035203 NM_002474 NP_002465 NM_022844 NP_074035
|
| Function |
Muscle contraction.
|
| Subcellular Location |
Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Thick filaments of the myofibrils.
|
| Tissue Specificity |
Smooth muscle; expressed in the umbilical artery, bladder, esophagus and trachea. Isoform 1 is mostly found in slowly contracting tonic muscles. {ECO:0000269|PubMed:16000639}.
|
| Top Pathways |
Tight junction, Vascular smooth muscle contraction
|