MYH11

Gene Symbol	MYH11
Entrez Gene	4629
Alt Symbol	AAT4, FAA4, SMHC, SMMHC
Species	Human
Gene Type	protein-coding
Description	myosin, heavy chain 11, smooth muscle
Other Description	myosin heavy chain 11|myosin heavy chain, smooth muscle isoform|myosin, heavy polypeptide 11, smooth muscle|myosin-11
Swissprots	O00396 Q3MIV8 D2JYH7 Q3MNF0 Q3MNF1 P35749 O94944 P78422
Accessions	AAC31665 AAC35212 ACZ58373 ACZ58374 EAW53924 EAW53925 EAW53926 EAW53927 EAW53928 EAW53929 EAW53930 P35749 AA552189 AB020673 BAA74889 AF013570 AAB69326 AF020091 AAB69327 AK125033 AK308389 AK311080 AY520816 AAS98910 AY520817 AAS98911 BC031040 AAH31040 BC080545 AAH80545 BC101677 AAI01678 BC104906 AAI04907 BC143364 AAI43365 BX489788 BX641087 CR749516 CAH18331 D10667 BAA36971 EU489063 ACB05996 S67238 AAB28950 S67240 AAB28951 X69292 CAA49154 XM_011522502 XP_011520804 XM_011546698 XP_011545000 NM_001040113 NP_001035202 NM_001040114 NP_001035203 NM_002474 NP_002465 NM_022844 NP_074035
Function	Muscle contraction.
Subcellular Location	Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Thick filaments of the myofibrils.
Tissue Specificity	Smooth muscle; expressed in the umbilical artery, bladder, esophagus and trachea. Isoform 1 is mostly found in slowly contracting tonic muscles. {ECO:0000269|PubMed:16000639}.
Top Pathways	Tight junction, Vascular smooth muscle contraction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MYH11 CRISPR/Cas9 KO Plasmid (h) - sc-400695 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MYH11 HDR Plasmid (h) - sc-400695-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MYH11 Double Nickase Plasmid (h) - sc-400695-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MYH11 Double Nickase Plasmid (h2) - sc-400695-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MYH11 CRISPR Activation Plasmid (h) - sc-400695-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MYH11 CRISPR Activation Plasmid (h2) - sc-400695-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MYH11 Lentiviral Activation Particles (h) - sc-400695-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MYH11 Lentiviral Activation Particles (h2) - sc-400695-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MYH11 siRNA (h) - sc-76523 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MYH11 shRNA Plasmid (h) - sc-76523-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MYH11 shRNA (h) Lentiviral Particles - sc-76523-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU133301 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14814 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14814 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13074 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr13074

MYH11 siRNA (Human) - CRH3056 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human Myh11 (NM_022844.2) - SHH347724 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human MYH11(NM_001040113.1) - SHH211151 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human MYH11(NM_001040114.1) - SHH211169 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human MYH11(NM_002474.2) - SHH211205 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human MYH11(NM_022844.2) - SHH211223 from Creative biogene Category siRNA Species Reactivities Human

Human MYH11 siRNA - orb263558 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

MYH11 shRNA Plasmid (Human) - CHH3056 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

MYH11 miRNA 3'UTR clone - MiUTR1H-06564 from Creative biogene Species Reactivities Human

MYH11 miRNA 3'UTR clone - MiUTR1H-06565 from Creative biogene Species Reactivities Human

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