| Gene Symbol |
POU6F2
|
| Entrez Gene |
11281
|
| Alt Symbol |
RPF-1, WT5, WTSL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
POU class 6 homeobox 2
|
| Other Description |
POU domain, class 6, transcription factor 2|Wilms tumor suppressor locus|retina-derived POU domain factor 1|retina-derived POU-domain factor-1
|
| Swissprots |
Q86UM6 P78425 C4AMB9 A4D1W2 P78424 Q9UDS7 Q75ME8
|
| Accessions |
AAB49727 AAC83404 AAP21873 AAS07475 EAL23992 EAW94116 EAW94117 P78424 AK309700 BC152915 AAI52916 DN991890 U91935 AAB49728 XM_011515113 XP_011513415 XM_011515114 XP_011513416 NM_001166018 NP_001159490 NM_007252 NP_009183
|
| Function |
Probable transcription factor likely to be involved in early steps in the differentiation of amacrine and ganglion cells. Recognizes and binds to the DNA sequence 5'-ATGCAAAT-3'. Isoform 1 does not bind DNA.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Tissue Specificity |
Expressed only within the CNS, where its expression is restricted to the medical habenulla, to a dispersed population of neurons in the dorsal hypothalamus, and to subsets of ganglion and amacrine cells in the retina. {ECO:0000269|PubMed:8601806}.
|
![Western Blot: POU6F2 Overexpression Lysate (Adult Normal) [NBP2-07515] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for POU6F2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2907_POU6F2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07515-img0001.jpg)