EIF3B

Gene Symbol	EIF3B
Entrez Gene	8662
Alt Symbol	EIF3-ETA, EIF3-P110, EIF3-P116, EIF3S9, PRT1
Species	Human
Gene Type	protein-coding
Description	eukaryotic translation initiation factor 3, subunit B
Other Description	eIF-3-eta|eIF3 p110|eIF3 p116|eukaryotic translation initiation factor 3 subunit 9|eukaryotic translation initiation factor 3 subunit B|eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD)|eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa|hPrt1|prt1 homolog
Swissprots	A4D208 Q9UMF9 Q2NL77 P55884
Accessions	AAP21880 EAL23951 EAL23952 EAW87237 EAW87238 EAW87239 EAW87240 EAW87241 P55884 AB209381 BAD92618 AI888128 AK093807 AK126670 AK127885 AK300967 BAG62591 AK302058 BAG63448 BC001173 AAH01173 BC009986 AAH09986 BC110865 AAI10866 BG325094 BM556863 BQ015102 BQ045103 BQ070291 U62583 AAB42010 U78525 AAC99479 XM_011515599 XP_011513901 XM_011515600 XP_011513902 XM_011515601 XP_011513903 NM_001037283 NP_001032360 NM_003751 NP_003742
Function	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. {ECO:0000269|PubMed:9388245}.
Subcellular Location	Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03001}.
Top Pathways	RNA transport

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human eIF3B peptide - ab41603 from Abcam Category Peptide

Human eIF3B peptide - ab41604 from Abcam Category Peptide

EIF3B Antibody Blocking Peptide - LS-E14777 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HPRT1 / HPRT Antibody Blocking Peptide - LS-E22322 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HPRT1 / HPRT Antibody Blocking Peptide - LS-E8424 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HPRT1 / HPRT Antibody Blocking Peptide - LS-E8425 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HPRT1 / HPRT Antibody Blocking Peptide - LS-E17534 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human HPRT Protein - H00003251-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human HPRT Protein - NBP1-45251 from Novus Biologicals Category Protein Prices $269.00, $629.00 Sizes 100 µg, 500 µg Source E. coli Species Human

EIF3B-Antibody-Center-Blocking-Peptide - BP9291c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human Hypoxanthine-Guanine Phosphoribosyltransferase protein - orb90146 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 5 μg, 25 μg Source E.coli Species Human

EIF3S9 Blocking Peptide - 33R-10226 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HPRT1 Blocking Peptide - 33R-8866 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

EIF3B fusion protein - ag0386 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

HPRT1 Human Protein - GWB-BSP209 from Genway Biotech Category Protein Prices $75.00, $165.00, $2,685.00 Sizes 5 μg, 20 μg, 1000 μg Source Escherichia Coli. Species Human

Recombinant Human Eukaryotic translation initiation factor 3 subunit B(EIF3B) ,p - CSB-YP007530HU CSB-EP007530HU CSB-BP007530HU CSB-MP007530HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

EIF3B / EIF3S9 (transcript variant 2) - TP300612 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

EIF3B / EIF3S9 (transcript variant 1) - TP311093 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

EIF3B Protein - NBP2-38597PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

HPRT Recombinant Protein Antigen - NBP1-92006PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

EIF3B Peptide, Human - M34GP04811H from Creative Peptides Category Peptide Source Synthetic. Species Human

HPRT1 Peptide, Human - M34GP07232H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Human HPRT Protein - NBP2-53063 from Novus Biologicals Category Protein Prices $109.00, $339.00 Sizes 20 µg, 100 µg Source E.coli (Bioactivity Validated) Species Human

Eukaryotic translation initiation factor 3 subunit B (EIF3B), partial, Recombinant Protein - MBS967154 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Eukaryotic translation initiation factor 3 subunit B (TIF32), Recombinant Protein - MBS1089945 from MyBioSource Category Protein Prices $970.00, $970.00, $1,195.00, $1,195.00, $1,460.00, $1,460.00, $1,925.00, $1,925.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

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