Gene Symbol | TRAK1 |
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Entrez Gene | 22906 |
Alt Symbol | MILT1, OIP106 |
Species | Human |
Gene Type | protein-coding |
Description | trafficking protein, kinesin binding 1 |
Other Description | 106 kDa O-GlcNAc transferase-interacting protein|O-linked N-acetylglucosamine transferase interacting protein 106|OGT(O-Glc-NAc transferase)-interacting protein 106 KDa|milton homolog 1|trafficking kinesin-binding protein 1 |
Swissprots | Q96B69 Q659B5 Q63HR0 Q9UPV9 J3KNT7 E9PDS2 |
Accessions | EAW64638 EAW64639 EAW64640 EAW64641 EAW64642 Q9UPV9 AA534633 AB028965 BAA82994 AK000754 AK023962 AK294221 BAH11704 AK295480 BAH12083 AK295848 BAH12201 AK316260 BAH14631 AL713787 CAH56394 AM392573 CAL37451 AM393596 CAL38473 AW157246 BC015922 AAH15922 BF527591 BG285410 BX647199 CAH56169 CD722736 DA193280 EU446989 ABZ92518 H05058 XM_005264956 XP_005265013 XM_005264957 XP_005265014 XM_005264958 XP_005265015 XM_005264959 XP_005265016 XM_005264960 XP_005265017 XM_005264962 XP_005265019 XM_005264963 XP_005265020 XM_006713028 XP_006713091 XM_006713029 XP_006713092 XM_006713030 XP_006713093 XM_006713031 XP_006713094 XM_011533487 XP_011531789 XM_011533488 XP_011531790 XM_011533489 XP_011531791 NM_001042646 NP_001036111 NM_001265608 NP_001252537 NM_001265609 NP_001252538 NM_001265610 NP_001252539 NM_014965 NP_055780 |
Function | Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors. {ECO:0000269|PubMed:18675823}. |
Subcellular Location | Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome. Note=Predominantly associated with early endosome. The localization to early endosomes depends on its interaction with HRS. Colocalizes with MGARP at the mitochondria. |
Tissue Specificity | High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined. {ECO:0000269|PubMed:18986759}. |
OIP106 (C-19) - sc-48616 from Santa Cruz Biotechnology
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Anti-TRAK1 antibody - ab89962 from Abcam
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Anti-TRAK1 antibody - ab28751 from Abcam
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Anti-TRAK1 Antibody (aa61-110) - LS-C117015 from LifeSpan Bioscience
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Anti-TRAK1 Antibody (aa467-516) - LS-C111566 from LifeSpan Bioscience
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Anti-TRAK1 Antibody (aa943-953) - LS-C55199 from LifeSpan Bioscience
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Anti-TRAK1 Antibody (C-Terminus) - LS-C155142 from LifeSpan Bioscience
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OIP106 Antibody - NBP1-56761 from Novus Biologicals
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OIP106 Antibody - NBP1-87890 from Novus Biologicals
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OIP106 Antibody - NB300-955 from Novus Biologicals
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OIP106 Antibody (1C5) - H00022906-M01A-200ul from Novus Biologicals
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OIP106 Antibody - H00022906-B01-50ul from Novus Biologicals
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TRAK1 Polyclonal Antibody - bs-5536R from Bioss
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Anti-OIP106/TRAK1 antibody produced in goat - SAB2500716 from Sigma-Aldrich
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Monoclonal Anti-TRAK1 antibody produced in mouse - SAB1412808 from Sigma-Aldrich
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Anti-TRAK1 antibody produced in rabbit - HPA005853 from Sigma-Aldrich
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Anti-TRAK1 antibody produced in rabbit - SAB2103753 from Sigma-Aldrich
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TRAK1 antibody - middle region (ARP54520_P050) - ARP54520_P050 from Aviva Systems Biology
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TRAK1 antibody - middle region (ARP54521_P050) - ARP54521_P050 from Aviva Systems Biology
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OIP106--TRAK1-Antibody - AF1753a from Abgent, a WuXi AppTec company
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OIP106 / TRAK1 antibody, C-term - GTX89610 from GeneTex
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TRAK1 Antibody (OABF01580) - OABF01580 from Aviva Systems Biology
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Goat Anti-OIP106 / TRAK1 Antibody (OAEB02122) - OAEB02122 from Aviva Systems Biology
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TRAK1 antibody - 70R-9271 from Fitzgerald
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TRAK1 antibody - orb4795 from Biorbyt
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