| Gene Symbol |
LTB4R2
|
| Entrez Gene |
56413
|
| Alt Symbol |
BLT2, BLTR2, JULF2, KPG_004, LTB4-R 2, LTB4-R2, NOP9
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
leukotriene B4 receptor 2
|
| Other Description |
LTB4 receptor JULF2|leukotriene B4 receptor BLT2|seven transmembrane receptor BLTR2
|
| Swissprots |
Q5KU28 Q9NPE5 Q9NPC1
|
| Accessions |
AAP23200 BAB00610 BAB89317 CAB96134 EAW66030 Q9NPC1 AB029892 BAA99553 AB032558 BAD83590 AB044402 BAA99539 AF277230 AAF81261 AF308571 AAG40857 AK304169 BAG65054 BC038437 BC119674 AAI19675 BC127643 AAI27644 BC172240 AAI72240 BC172548 AAI72548 DC408599 NM_001164693 NM_001164692 NP_001158164 NM_019839 NP_062813
|
| Function |
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Widely expressed.
|
| Top Pathways |
Calcium signaling pathway, Neuroactive ligand-receptor interaction
|