| Gene Symbol |
C10orf90
|
| Entrez Gene |
118611
|
| Alt Symbol |
FATS, bA422P15.2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chromosome 10 open reading frame 90
|
| Other Description |
centrosomal protein C10orf90|fragile-site associated tumor suppressor homolog
|
| Swissprots |
Q8NCV5 B9EIQ9 Q96M02 Q8WU75 Q5JRP6 Q5T023
|
| Accessions |
EAW49200 EAW49201 EAW49202 Q96M02 AF435960 AAM20911 AK057500 BAB71512 AK093093 AK297577 BAG59968 AK308357 AK309217 AL705062 BC021140 AAH21140 BC034828 BC140898 AAI40899 BC146869 AAI46870 BC156058 AAI56059 BC156941 AAI56942 XM_005269491 XP_005269548 XM_005269492 XP_005269549 XM_011539216 XP_011537518 XM_011539217 XP_011537519 XM_011539218 XP_011537520 XM_011539219 XP_011537521 XM_011539220 XP_011537522 XM_011539221 XP_011537523 XM_011539222 XP_011537524 XM_011539223 XP_011537525 XM_011539224 XP_011537526 XM_011539225 XP_011537527 XM_011539226 XP_011537528 XM_011539227 XP_011537529 XM_011539228 XP_011537530 XM_011539229 XP_011537531 XM_011539230 XP_011537532 XM_011539231 XP_011537533 XM_011539232 XP_011537534 XM_011539233 XP_011537535 XM_011539234 XP_011537536 XM_011539235 XP_011537537 XM_011539236 XP_011537538 XM_011539237 XP_011537539 XR_945591 NM_001004298 NP_001004298
|
| Function |
Tumor suppressor that is required to sustain G2/M checkpoint after DNA damage. Mediates CDKN1A/p21 protein stability in a ubiquitin-independent manner (By similarity). May have a role in the assembly of primary cilia. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:20844083}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20844083}. Note=Localizes to the actin cytoskeleton in a proportion of cells. Colocalizes with centriolar acetylated tubulin.
|