Gene Symbol | C10orf90 |
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Entrez Gene | 118611 |
Alt Symbol | FATS, bA422P15.2 |
Species | Human |
Gene Type | protein-coding |
Description | chromosome 10 open reading frame 90 |
Other Description | centrosomal protein C10orf90|fragile-site associated tumor suppressor homolog |
Swissprots | Q8NCV5 B9EIQ9 Q96M02 Q8WU75 Q5JRP6 Q5T023 |
Accessions | EAW49200 EAW49201 EAW49202 Q96M02 AF435960 AAM20911 AK057500 BAB71512 AK093093 AK297577 BAG59968 AK308357 AK309217 AL705062 BC021140 AAH21140 BC034828 BC140898 AAI40899 BC146869 AAI46870 BC156058 AAI56059 BC156941 AAI56942 XM_005269491 XP_005269548 XM_005269492 XP_005269549 XM_011539216 XP_011537518 XM_011539217 XP_011537519 XM_011539218 XP_011537520 XM_011539219 XP_011537521 XM_011539220 XP_011537522 XM_011539221 XP_011537523 XM_011539222 XP_011537524 XM_011539223 XP_011537525 XM_011539224 XP_011537526 XM_011539225 XP_011537527 XM_011539226 XP_011537528 XM_011539227 XP_011537529 XM_011539228 XP_011537530 XM_011539229 XP_011537531 XM_011539230 XP_011537532 XM_011539231 XP_011537533 XM_011539232 XP_011537534 XM_011539233 XP_011537535 XM_011539234 XP_011537536 XM_011539235 XP_011537537 XM_011539236 XP_011537538 XM_011539237 XP_011537539 XR_945591 NM_001004298 NP_001004298 |
Function | Tumor suppressor that is required to sustain G2/M checkpoint after DNA damage. Mediates CDKN1A/p21 protein stability in a ubiquitin-independent manner (By similarity). May have a role in the assembly of primary cilia. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:20844083}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20844083}. Note=Localizes to the actin cytoskeleton in a proportion of cells. Colocalizes with centriolar acetylated tubulin. |
C10orf90 CRISPR/Cas9 KO Plasmid (h) - sc-414129 from Santa Cruz Biotechnology
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C10orf90 HDR Plasmid (h) - sc-414129-HDR from Santa Cruz Biotechnology
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C10orf90 Double Nickase Plasmid (h) - sc-414129-NIC from Santa Cruz Biotechnology
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C10orf90 Double Nickase Plasmid (h2) - sc-414129-NIC-2 from Santa Cruz Biotechnology
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C10orf90 CRISPR Activation Plasmid (h) - sc-414129-ACT from Santa Cruz Biotechnology
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C10orf90 CRISPR Activation Plasmid (h2) - sc-414129-ACT-2 from Santa Cruz Biotechnology
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C10orf90 Lentiviral Activation Particles (h) - sc-414129-LAC from Santa Cruz Biotechnology
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C10orf90 Lentiviral Activation Particles (h2) - sc-414129-LAC-2 from Santa Cruz Biotechnology
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C10orf90 siRNA (h) - sc-90552 from Santa Cruz Biotechnology
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C10orf90 shRNA Plasmid (h) - sc-90552-SH from Santa Cruz Biotechnology
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C10orf90 shRNA (h) Lentiviral Particles - sc-90552-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU089911 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4176 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4176 from Sigma-Aldrich
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C10orf90 siRNA (Human) - CRJ4591 from Cohesion Biosciences
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C10orf90 - MBS827483 from MyBioSource
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shRNA set against Human C10orf90 (NM_001004298.2) - SHH248778 from Creative biogene
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Human C10orf90 siRNA - orb275092 from Biorbyt
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C10orf90 shRNA Plasmid (Human) - CHJ4591 from Cohesion Biosciences
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C10ORF90 miRNA 3'UTR clone - MiUTR1H-01022 from Creative biogene
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