| Gene Symbol |
TMEM231
|
| Entrez Gene |
79583
|
| Alt Symbol |
ALYE870, JBTS20, MKS11, PRO1886
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protein 231
|
| Other Description |
-
|
| Swissprots |
G5E9E3 A6NDZ6 Q6UWW5 Q6P450 Q9H6L2 B3KU85 A0JLU1
|
| Accessions |
EAW95632 EAW95633 EAW95634 Q9H6L2 AK025820 BAB15244 AK057689 AK096650 BAG53347 AK290483 BAF83172 AK298994 BAH12919 AK307263 AY358612 AAQ88975 BC010609 AAH10609 BC016401 AAH16401 BC063677 AAH63677 BM973146 BU173659 DA498255 DB082071 DC330418 NM_001077416 NP_001070884 NM_001077418 NP_001070886 NR_074083
|
| Function |
Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell projection, cilium membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Localizes to the transition zone of primary cilia; SEPT2 is required for localization to the transition zone. {ECO:0000250}.
|
![Western Blot: TMEM231 Overexpression Lysate (Adult Normal) [NBP2-11453] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TMEM231.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1910_TMEM231%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-11453-img0001.jpg)
![Western Blot: TMEM231 Overexpression Lysate (Adult Normal) [NBP2-10644] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TMEM231.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2375_TMEM231%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10644-img0001.jpg)