Gene Symbol | TMEM231 |
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Entrez Gene | 79583 |
Alt Symbol | ALYE870, JBTS20, MKS11, PRO1886 |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protein 231 |
Other Description | - |
Swissprots | G5E9E3 A6NDZ6 Q6UWW5 Q6P450 Q9H6L2 B3KU85 A0JLU1 |
Accessions | EAW95632 EAW95633 EAW95634 Q9H6L2 AK025820 BAB15244 AK057689 AK096650 BAG53347 AK290483 BAF83172 AK298994 BAH12919 AK307263 AY358612 AAQ88975 BC010609 AAH10609 BC016401 AAH16401 BC063677 AAH63677 BM973146 BU173659 DA498255 DB082071 DC330418 NM_001077416 NP_001070884 NM_001077418 NP_001070886 NR_074083 |
Function | Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity). {ECO:0000250}. |
Subcellular Location | Cell projection, cilium membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Localizes to the transition zone of primary cilia; SEPT2 is required for localization to the transition zone. {ECO:0000250}. |
TMEM231 CRISPR/Cas9 KO Plasmid (h) - sc-413179 from Santa Cruz Biotechnology
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TMEM231 HDR Plasmid (h) - sc-413179-HDR from Santa Cruz Biotechnology
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TMEM231 Double Nickase Plasmid (h) - sc-413179-NIC from Santa Cruz Biotechnology
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TMEM231 Double Nickase Plasmid (h2) - sc-413179-NIC-2 from Santa Cruz Biotechnology
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TMEM231 CRISPR Activation Plasmid (h) - sc-413179-ACT from Santa Cruz Biotechnology
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TMEM231 CRISPR Activation Plasmid (h2) - sc-413179-ACT-2 from Santa Cruz Biotechnology
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TMEM231 Lentiviral Activation Particles (h) - sc-413179-LAC from Santa Cruz Biotechnology
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TMEM231 Lentiviral Activation Particles (h2) - sc-413179-LAC-2 from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU218951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21609 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21609 from Sigma-Aldrich
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TMEM231 siRNA (Human) - CRJ2407 from Cohesion Biosciences
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TMEM231 - MBS8232963 from MyBioSource
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shRNA set against Human FLJ22167(NM_001077416.1) - SHH061913 from Creative biogene
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shRNA set against Human FLJ22167(NM_001077419.1) - SHH061919 from Creative biogene
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shRNA set against Human FLJ22167(NM_001077418.1) - SHH061937 from Creative biogene
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shRNA set against Human FLJ22167(NM_001077416.1) - SHH061955 from Creative biogene
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Human TMEM231 siRNA - orb272908 from Biorbyt
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TMEM231 shRNA Plasmid (Human) - CHJ2407 from Cohesion Biosciences
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TMEM231 miRNA 3'UTR clone - MiUTR1H-03712 from Creative biogene
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TMEM231 miRNA 3'UTR clone - MiUTR1H-03713 from Creative biogene
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TMEM231 miRNA 3'UTR clone - MiUTR1H-03714 from Creative biogene
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