| Gene Symbol |
RNPC3
|
| Entrez Gene |
55599
|
| Alt Symbol |
RBM40, RNP, SNRNP65
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RNA-binding region (RNP1, RRM) containing 3
|
| Other Description |
RNA recognition protein|RNA-binding motif protein 40|RNA-binding protein 40|RNA-binding region-containing protein 3|U11/U12 small nuclear ribonucleoprotein 65 kDa protein|U11/U12 snRNP 65 kDa protein|U11/U12 snRNP 65K|U11/U12-65K
|
| Swissprots |
Q9NXX2 Q5TZ87 Q96LT9 A8K1C9 Q9NSU7 Q96FK7 Q96JI8 D3DT74
|
| Accessions |
EAW72901 EAW72905 EAW72906 Q96LT9 AK000015 BAA90885 AK057799 BAB71580 AK289844 BAF82533 AL137730 CAB70897 AY099329 AAM45139 BC010697 AAH10697 BK005195 DAA05493 CN386195 NM_017619 NP_060089
|
| Function |
Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA. {ECO:0000269|PubMed:16096647, ECO:0000269|PubMed:19447915}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:14974681}.
|
| Tissue Specificity |
Highly expressed in pancreas and kidney. Detected at lower levels in heart, brain, placenta, lung, liver, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. {ECO:0000269|PubMed:14974681}.
|
![Western Blot: RNPC3 Overexpression Lysate (Adult Normal) [NBL1-15469] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RNPC3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/8709_RNPC3%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-15469-img0002.jpg)