Gene Symbol | RNPC3 |
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Entrez Gene | 55599 |
Alt Symbol | RBM40, RNP, SNRNP65 |
Species | Human |
Gene Type | protein-coding |
Description | RNA-binding region (RNP1, RRM) containing 3 |
Other Description | RNA recognition protein|RNA-binding motif protein 40|RNA-binding protein 40|RNA-binding region-containing protein 3|U11/U12 small nuclear ribonucleoprotein 65 kDa protein|U11/U12 snRNP 65 kDa protein|U11/U12 snRNP 65K|U11/U12-65K |
Swissprots | Q9NXX2 Q5TZ87 Q96LT9 A8K1C9 Q9NSU7 Q96FK7 Q96JI8 D3DT74 |
Accessions | EAW72901 EAW72905 EAW72906 Q96LT9 AK000015 BAA90885 AK057799 BAB71580 AK289844 BAF82533 AL137730 CAB70897 AY099329 AAM45139 BC010697 AAH10697 BK005195 DAA05493 CN386195 NM_017619 NP_060089 |
Function | Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA. {ECO:0000269|PubMed:16096647, ECO:0000269|PubMed:19447915}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:14974681}. |
Tissue Specificity | Highly expressed in pancreas and kidney. Detected at lower levels in heart, brain, placenta, lung, liver, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. {ECO:0000269|PubMed:14974681}. |
U11/U12 snRNP 65K CRISPR/Cas9 KO Plasmid (h) - sc-409455 from Santa Cruz Biotechnology
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U11/U12 snRNP 65K HDR Plasmid (h) - sc-409455-HDR from Santa Cruz Biotechnology
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U11/U12 snRNP 65K Double Nickase Plasmid (h) - sc-409455-NIC from Santa Cruz Biotechnology
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U11/U12 snRNP 65K Double Nickase Plasmid (h2) - sc-409455-NIC-2 from Santa Cruz Biotechnology
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U11/U12 snRNP 65K CRISPR Activation Plasmid (h) - sc-409455-ACT from Santa Cruz Biotechnology
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U11/U12 snRNP 65K CRISPR Activation Plasmid (h2) - sc-409455-ACT-2 from Santa Cruz Biotechnology
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U11/U12 snRNP 65K Lentiviral Activation Particles (h) - sc-409455-LAC from Santa Cruz Biotechnology
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U11/U12 snRNP 65K Lentiviral Activation Particles (h2) - sc-409455-LAC-2 from Santa Cruz Biotechnology
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U11/U12 snRNP 65K siRNA (h) - sc-88143 from Santa Cruz Biotechnology
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U11/U12 snRNP 65K shRNA Plasmid (h) - sc-88143-SH from Santa Cruz Biotechnology
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U11/U12 snRNP 65K shRNA (h) Lentiviral Particles - sc-88143-V from Santa Cruz Biotechnology
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RNPC3 RNAi - H00055599-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN18452 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18452 from Sigma-Aldrich
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RNPC3 siRNA (Human) - CRJ0760 from Cohesion Biosciences
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RNPC3 - MBS8240020 from MyBioSource
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shRNA set against Human RNPC3 (NM_017619.3) - SHH397521 from Creative biogene
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shRNA set against Human RNPC3(NM_017619.3) - SHR188772 from Creative biogene
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Human RNPC3 siRNA - orb271261 from Biorbyt
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RNPC3 shRNA Plasmid (Human) - CHJ0760 from Cohesion Biosciences
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RNPC3 miRNA 3'UTR clone - MiUTR1H-08915 from Creative biogene
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