| Gene Symbol |
LETM1
|
| Entrez Gene |
3954
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
leucine zipper-EF-hand containing transmembrane protein 1
|
| Other Description |
LETM1 and EF-hand domain-containing protein 1, mitochondrial|Mdm38 homolog
|
| Swissprots |
Q9UF65 B4DED2 O95202
|
| Accessions |
EAW82560 EAW82561 O95202 AF061025 AAD13138 AK293572 BAG57043 AK310563 AL133650 CAB63769 BC014500 AAH14500 BC021208 AAH21208 DQ893606 ABM84532 XM_005247970 XP_005248027 XM_006713884 XP_006713947 NM_012318 NP_036450
|
| Function |
Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization. {ECO:0000269|PubMed:18628306}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:14706454, ECO:0000269|PubMed:15138253, ECO:0000269|PubMed:18628306}; Single-pass membrane protein {ECO:0000269|PubMed:14706454, ECO:0000269|PubMed:15138253, ECO:0000269|PubMed:18628306}.
|
![Western Blot: LETM1 Overexpression Lysate (Adult Normal) [NBP2-04334] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LETM1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/23182_LETM1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-04334-img0001.jpg)