Gene Symbol | FOXD3 |
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Entrez Gene | 27022 |
Alt Symbol | AIS1, Genesis, HFH2, VAMAS2 |
Species | Human |
Gene Type | protein-coding |
Description | forkhead box D3 |
Other Description | HNF3/FH transcription factor genesis|forkhead box protein D3 |
Swissprots | Q9UDD1 Q9UJU5 Q9BYM2 |
Accessions | AAF05844 EAX06575 Q9UJU5 AF086235 BC172266 AAI72266 BC172572 AAI72572 L12142 AAK13574 NM_012183 NP_036315 |
Function | Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis. {ECO:0000269|PubMed:11891324}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined. {ECO:0000269|PubMed:8499623}. |
Human FOXD3 full length protein - ab134848 from Abcam
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FOXD3 Antibody Blocking Peptide - LS-E11429 from LifeSpan Bioscience
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Recombinant Human FOXD3 - FOXD3-1062H from Creative Biomart
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FOXD3 Blocking Peptide - CBP3942 from Cohesion Biosciences
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FoxD3 (R233) Peptide - BS2163P from Bioworld Technology
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Recombinant Human Forkhead box protein D3(FOXD3) - CSB-YP890729HU CSB-EP890729HU CSB-BP890729HU CSB-MP890729HU from Cusabio
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FOXD3 Peptide - abx164649 from Abbexa
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FOXD3 Blocking Peptide - abx162435 from Abbexa
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FOXD3 Peptide, Human - M34GP05844H from Creative Peptides
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Forkhead box protein D3 (FOXD3), Recombinant Protein - MBS1366689 from MyBioSource
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FOXD3 fusion protein - Ag27260 from Proteintech Group
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FOXD3 peptide - orb256829 from Biorbyt
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