| Gene Symbol |
Dmrt2
|
| Entrez Gene |
226049
|
| Alt Symbol |
Terra
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
doublesex and mab-3 related transcription factor 2
|
| Other Description |
dmrt2|doublesex- and mab-3-related transcription factor 2|doublesex-like 2 protein|terra homolog
|
| Swissprots |
Q9WVM0 Q9JJU0 Q3USI4 Q3USI7 Q9JJU3 Q8K185 Q8BG36
|
| Accessions |
CAB93343 CAB93344 CAB93345 CAB93346 EDL41636 Q8BG36 AF080623 AAD38425 AF539811 AAN77205 AK044891 BAC32130 AK140337 BAE24344 AK140347 BAE24347 BC027669 AAH27669 XM_006526982 XP_006527045 XM_006526983 XP_006527046 NM_145831 NP_665830
|
| Function |
Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome. Is not required for sex determination and/or differentiation in embryonic development. Also not involved in symmetric somite formation and hence does not regulate the laterality pathway that controls left- right asymmetric organ positioning. {ECO:0000269|PubMed:10021344, ECO:0000269|PubMed:16387292, ECO:0000269|PubMed:17605809, ECO:0000269|PubMed:20368965, ECO:0000269|PubMed:21203428}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00070, ECO:0000269|PubMed:17605809}.
|
| Tissue Specificity |
Expressed in testis. {ECO:0000269|PubMed:12609607, ECO:0000269|PubMed:20368965}.
|