Gene Symbol |
PRDX2
|
Entrez Gene |
7001
|
Alt Symbol |
HEL-S-2a, NKEF-B, NKEFB, PRP, PRX2, PRXII, PTX1, TDPX1, TPX1, TSA
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
peroxiredoxin 2
|
Other Description |
epididymis secretory sperm binding protein Li 2a|natural killer cell-enhancing factor B|peroxiredoxin-2|thiol-specific antioxidant 1|thioredoxin peroxidase 1|thioredoxin-dependent peroxide reductase 1|torin
|
Swissprots |
P31945 P32119 Q92763 P35701 A8K0C0 Q9UC23 Q6FHG4 P32118
|
Accessions |
ABB02182 EAW84308 EAW84309 EAW84310 EAW84311 EAW84312 P32119 AK022395 AK289485 BAF82174 AK293957 BAG57331 AL600939 BC000452 AAH00452 BC003022 AAH03022 BC039428 AAH39428 BC064138 BG705975 BP248561 BQ549456 CR450356 CAG29352 CR541789 CAG46588 DQ895403 ABM86329 EU176327 ABW03778 EU668325 ACF94478 L19185 AAA50465 X82321 CAA57764 Z22548 CAA80269 NM_005809 NP_005800 NM_181737 NM_181738
|
Function |
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).
|
Subcellular Location |
Cytoplasm.
|