PRDX2

Gene Symbol PRDX2
Entrez Gene 7001
Alt Symbol HEL-S-2a, NKEF-B, NKEFB, PRP, PRX2, PRXII, PTX1, TDPX1, TPX1, TSA
Species Human
Gene Type protein-coding
Description peroxiredoxin 2
Other Description epididymis secretory sperm binding protein Li 2a|natural killer cell-enhancing factor B|peroxiredoxin-2|thiol-specific antioxidant 1|thioredoxin peroxidase 1|thioredoxin-dependent peroxide reductase 1|torin
Swissprots P31945 P32119 Q92763 P35701 A8K0C0 Q9UC23 Q6FHG4 P32118
Accessions ABB02182 EAW84308 EAW84309 EAW84310 EAW84311 EAW84312 P32119 AK022395 AK289485 BAF82174 AK293957 BAG57331 AL600939 BC000452 AAH00452 BC003022 AAH03022 BC039428 AAH39428 BC064138 BG705975 BP248561 BQ549456 CR450356 CAG29352 CR541789 CAG46588 DQ895403 ABM86329 EU176327 ABW03778 EU668325 ACF94478 L19185 AAA50465 X82321 CAA57764 Z22548 CAA80269 NM_005809 NP_005800 NM_181737 NM_181738
Function Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).
Subcellular Location Cytoplasm.

PRX (C-18) - sc-23970 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PRX (C-18): sc-23970. Western blot analysis of PRX expression in rat brain tissue extract.

PRX (H-10) - sc-373962 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PRX (H-10): sc-373962. Western blot analysis of PRX expression in MCF7 (A) and K-562 (B) whole cell lysates.

PRX (G-10) - sc-137212 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PRX (G-10): sc-137212. Western blot analysis of PRX II expression in non-transfected 293T: sc-117752 (A), mouse PRX II transfected 293T: sc-122808 (B) and MCF7 (C) whole cell lysates.

PRX (H-198) - sc-33574 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PRX (H-198): sc-33574. Immunofluorescence staining of normal mouse intestine frozen section showing cytoplasmic staining.

PRX (L-20) - sc-23969 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PRX (L-20): sc-23969. Immunoperoxidase staining of formalin fixed, paraffin-embedded human breast tumor showing cytoplasmic localization

PRX (A-6) - sc-137150 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PRX (A-6): sc-137150. Western blot analysis of PRX II expression in non-transfected 293T: sc-117752 (A), mouse PRX II transfected 293T: sc-122808 (B) and MCF7 (C) whole cell lysates.

PRX II (M-40) - sc-33572 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PRX II (M-40): sc-33572. Western blot analysis of PRX II expression in SK-BR-3 (A), SK-N-SH (B), MDA-MB-231 (C) and MCF7 (D) whole cell lysates.

PRX II (N-13) - sc-23967 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PRX II (N-13): sc-23967. Western blot analysis of PRX II expression in MCF7 (A), SK-N-SH (B) and K-562 (C) whole cell lysates and rat heart (D) and mouse brain (E) tissue extracts.

Anti-Peroxiredoxin 2 antibody - ab15572 from Abcam

Prices $394.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Staining of Peroxiredoxin 2 in TSU PR1 cells using ab15572.

Anti-Peroxiredoxin 2 antibody - ab71533 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Peroxiredoxin 2 antibody (ab71533) at 1/2000 dilutionLane 1 : HeLa cell lysateLane 2 : NIH3T3 cell lysateLane 3 : C6 cell lysateLane 4 : A431 cell lysate

Anti-Peroxiredoxin 2 antibody [1E8] - ab50862 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E8
All lanes : Anti-Peroxiredoxin 2 antibody [1E8] (ab50862) at 1/2000 dilutionLane 1 : HeLa cell lysateLane 2 : 293T cell lysateLane 3 : SH-SY5Y cell lysateLane 4 : HepG2 cell lysate

Anti-Peroxiredoxin 2 antibody [EPR5154] - ab109367 from Abcam

Prices $398.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5154
Overlay histogram showing HeLa cells stained with ab109367 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab109367, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-Peroxiredoxin 2 antibody [EPR5154] (Alexa Fluor® 488) - ab197536 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5154
ab197536 staining Peroxiredoxin 2 in Hek293 cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1%PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab197536 at a 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at a 1/250 dilution (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Peroxiredoxin 2 antibody [EPR5154] (Alexa Fluor® 647) - ab197041 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5154
ab197041 staining Peroxiredoxin in Hek293 cells. The cells were fixed with 100% methanol (5 min), permeabilized in 0.1% Triton X-100 for 5 minutes and then blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated with ab197041 at 1/100 dilution (shown in red) and ab195887, Mouse monoclonal [DM1A] to alpha Tubulin (Alexa Fluor® 488, shown in green) at 1/167 dilution, overnight at +4°C. Nuclear DNA was labelled in blue with DAPI. This product also gave a positive signal under the same testing conditions in Hek293 cells fixed with 4% formaldehyde (10 min).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Peroxiredoxin 2 antibody [EPR5154] (HRP) - ab197042 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5154
All lanes : Anti-Peroxiredoxin 2 antibody [EPR5154] (HRP) (ab197042) at 1/3000 dilutionLane 1 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate (ab52256)Lane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate (ab150035)Lane 3 : LNCaP (Human prostate adenocarcinoma cell line) Whole Cell Lysate - clone FGCLane 4 : SHSY-5Y (Human neuroblastoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.developed using the ECL techniquePerformed under reducing conditions.

Anti-Peroxiredoxin 2 antibody [EPR5155] - ab133481 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5155
Overlay histogram showing HeLa cells stained with ab133481 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab133481, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-PRDX2 / Peroxiredoxin 2 Antibody IHC-plus™ - LS-B7837 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Anti-PRDX2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7837 dilution 1:200.

Anti-PRDX2 / Peroxiredoxin 2 Antibody (aa103-114) - LS-C9563 from LifeSpan Bioscience

Prices $515.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDX2 / Peroxiredoxin 2 Antibody (aa186-198) - LS-C34674 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PRDX2 / Peroxiredoxin 2 Antibody (aa60-190) - LS-C39600 from LifeSpan Bioscience

Prices $475.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-PRDX2 / Peroxiredoxin 2 Antibody (C-Terminus) - LS-C74281 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal

Anti-PRDX2 / Peroxiredoxin 2 Antibody - LS-C131360 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PRDX2 / Peroxiredoxin 2 Antibody - LS-C131361 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PRDX2 / Peroxiredoxin 2 Antibody - LS-C131363 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PRDX2 / Peroxiredoxin 2 Antibody - LS-C131362 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
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