| Gene Symbol |
ABHD3
|
| Entrez Gene |
171586
|
| Alt Symbol |
LABH3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
abhydrolase domain containing 3
|
| Other Description |
abhydrolase domain-containing protein 3|alpha/beta hydrolase domain containing protein 3|lung alpha/beta hydrolase 3|phospholipase ABHD3
|
| Swissprots |
Q8WU67 O43411 B7Z5C2 B0YIV0
|
| Accessions |
ACA05928 EAX01131 Q8WU67 AF007152 AAC19155 AK024880 AK024992 AK298728 BAH12858 AV654056 BC021196 AAH21196 BG547174 BI918326 CR627346 DB126083 HQ448233 ADQ32713 XM_011525847 XP_011524149 XM_011525848 XP_011524150 XM_011525849 XP_011524151 XR_243847 XR_935209 XR_935210 NM_001308256 NP_001295185 NM_001308257 NP_001295186 NM_138340 NP_612213
|
| Function |
Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain- containing and oxidatively truncated phospholipids. {ECO:0000269|PubMed:21926997}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
![Western Blot: ABHD3 Overexpression Lysate (Adult Normal) [NBL1-07197] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ABHD3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8504_ABHD3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07197-img0002.jpg)