Gene Symbol | ABHD3 |
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Entrez Gene | 171586 |
Alt Symbol | LABH3 |
Species | Human |
Gene Type | protein-coding |
Description | abhydrolase domain containing 3 |
Other Description | abhydrolase domain-containing protein 3|alpha/beta hydrolase domain containing protein 3|lung alpha/beta hydrolase 3|phospholipase ABHD3 |
Swissprots | Q8WU67 O43411 B7Z5C2 B0YIV0 |
Accessions | ACA05928 EAX01131 Q8WU67 AF007152 AAC19155 AK024880 AK024992 AK298728 BAH12858 AV654056 BC021196 AAH21196 BG547174 BI918326 CR627346 DB126083 HQ448233 ADQ32713 XM_011525847 XP_011524149 XM_011525848 XP_011524150 XM_011525849 XP_011524151 XR_243847 XR_935209 XR_935210 NM_001308256 NP_001295185 NM_001308257 NP_001295186 NM_138340 NP_612213 |
Function | Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain- containing and oxidatively truncated phospholipids. {ECO:0000269|PubMed:21926997}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
ABHD3 CRISPR/Cas9 KO Plasmid (h) - sc-414947 from Santa Cruz Biotechnology
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ABHD3 HDR Plasmid (h) - sc-414947-HDR from Santa Cruz Biotechnology
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ABHD3 Double Nickase Plasmid (h) - sc-414947-NIC from Santa Cruz Biotechnology
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ABHD3 Double Nickase Plasmid (h2) - sc-414947-NIC-2 from Santa Cruz Biotechnology
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ABHD3 CRISPR Activation Plasmid (h) - sc-414947-ACT from Santa Cruz Biotechnology
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ABHD3 CRISPR Activation Plasmid (h2) - sc-414947-ACT-2 from Santa Cruz Biotechnology
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ABHD3 Lentiviral Activation Particles (h) - sc-414947-LAC from Santa Cruz Biotechnology
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ABHD3 Lentiviral Activation Particles (h2) - sc-414947-LAC-2 from Santa Cruz Biotechnology
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ABHD3 siRNA (h) - sc-72417 from Santa Cruz Biotechnology
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ABHD3 shRNA Plasmid (h) - sc-72417-SH from Santa Cruz Biotechnology
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ABHD3 shRNA (h) Lentiviral Particles - sc-72417-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU034351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2664 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2664 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06172 from Sigma-Aldrich
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ABHD3 siRNA (Human) - CRJ6150 from Cohesion Biosciences
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ABHD3 - MBS8237530 from MyBioSource
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shRNA set against Human ABHD3 (NM_138340.4) - SHH229514 from Creative biogene
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Human ABHD3 siRNA - orb276651 from Biorbyt
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ABHD3 shRNA Plasmid (Human) - CHJ6150 from Cohesion Biosciences
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ABHD3 miRNA 3'UTR clone - MiUTR3H-12345 from Creative biogene
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