| Gene Symbol |
Mutyh
|
| Entrez Gene |
70603
|
| Alt Symbol |
5730495A01Rik, Mutyha, Mutyhalpha, Mutyhb, Mutyhbeta, Mutyhc, Myh
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
mutY homolog (E. coli)
|
| Other Description |
A/G-specific adenine DNA glycosylase|adenine-DNA glycosylase|mMYH|mutY homolog alpha|the full-length form type A, 5' region
|
| Swissprots |
A2AGE3 Q99P21
|
| Accessions |
EDL30581 EDL30582 EDL30583 Q99P21 AB117937 BAC98379 AB117938 BAC98380 AB117939 BAC98381 AK017730 AK049542 BAC33800 AK077546 AK156790 BAE33857 AY007717 AAG16632 BB090873 BC057942 AAH57942 CX213088 XM_006503392 XP_006503455 XM_006503393 XP_006503456 XM_006503394 XP_006503457 XM_011240613 XP_011238915 NM_001159581 NP_001153053 NM_133250 NP_573513
|
| Function |
Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2- OH-A DNA glycosylase activities (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|
| Top Pathways |
Base excision repair
|
