Gene Symbol | Mutyh |
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Entrez Gene | 70603 |
Alt Symbol | 5730495A01Rik, Mutyha, Mutyhalpha, Mutyhb, Mutyhbeta, Mutyhc, Myh |
Species | Mouse |
Gene Type | protein-coding |
Description | mutY homolog (E. coli) |
Other Description | A/G-specific adenine DNA glycosylase|adenine-DNA glycosylase|mMYH|mutY homolog alpha|the full-length form type A, 5' region |
Swissprots | A2AGE3 Q99P21 |
Accessions | EDL30581 EDL30582 EDL30583 Q99P21 AB117937 BAC98379 AB117938 BAC98380 AB117939 BAC98381 AK017730 AK049542 BAC33800 AK077546 AK156790 BAE33857 AY007717 AAG16632 BB090873 BC057942 AAH57942 CX213088 XM_006503392 XP_006503455 XM_006503393 XP_006503456 XM_006503394 XP_006503457 XM_011240613 XP_011238915 NM_001159581 NP_001153053 NM_133250 NP_573513 |
Function | Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2- OH-A DNA glycosylase activities (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. |
Top Pathways | Base excision repair |
MUTYH CRISPR/Cas9 KO Plasmid (m) - sc-427755 from Santa Cruz Biotechnology
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MUTYH HDR Plasmid (m) - sc-427755-HDR from Santa Cruz Biotechnology
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MUTYH Double Nickase Plasmid (m) - sc-427755-NIC from Santa Cruz Biotechnology
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MUTYH Double Nickase Plasmid (m2) - sc-427755-NIC-2 from Santa Cruz Biotechnology
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MUTYH CRISPR Activation Plasmid (m) - sc-427755-ACT from Santa Cruz Biotechnology
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MUTYH CRISPR Activation Plasmid (m2) - sc-427755-ACT-2 from Santa Cruz Biotechnology
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MUTYH Lentiviral Activation Particles (m) - sc-427755-LAC from Santa Cruz Biotechnology
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MUTYH Lentiviral Activation Particles (m2) - sc-427755-LAC-2 from Santa Cruz Biotechnology
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MUTYH siRNA (m) - sc-45816 from Santa Cruz Biotechnology
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MUTYH shRNA Plasmid (m) - sc-45816-SH from Santa Cruz Biotechnology
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MUTYH shRNA (m) Lentiviral Particles - sc-45816-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU057111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN36023 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36023 from Sigma-Aldrich
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MUTYH siRNA (Mouse) - CRM8285 from Cohesion Biosciences
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shRNA set against Mouse MUTYH (NM_133250.2) - SHH347236 from Creative biogene
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shRNA set against Mouse Mutyh(NM_001159581.1) - SHH209243 from Creative biogene
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Mouse MUTYH siRNA - orb287761 from Biorbyt
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MUTYH shRNA Plasmid (Mouse) - CHM8285 from Cohesion Biosciences
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MUTYH miRNA 3'UTR clone - MiUTR1M-07407 from Creative biogene
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