DBT

Gene Symbol	DBT
Entrez Gene	1629
Alt Symbol	BCATE2, BCKAD-E2, BCKADE2, BCOADC-E2, E2, E2B
Species	Human
Gene Type	protein-coding
Description	dihydrolipoamide branched chain transacylase E2
Other Description	52 kDa mitochondrial autoantigen of primary biliary cirrhosis|BCKAD E2 subunit|E2 component of branched chain alpha-keto acid dehydrogenase complex|branched chain 2-oxo-acid dehydrogenase complex component E2|branched chain acyltransferase, E2 component|branched-chain alpha-keto acid dehydrogenase complex component E2|dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex|dihydrolipoyl transacylase|dihydrolipoyllysine-residue (2-methylpropanoyl)transferase|lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial|lipoamide acyltransferase component of mitochondrial branched-chain alpha-keto acid dehydrogenase complex|mitochondrial branched chain alpha-keto acid dehydrogenase transacylase subunit (E2b)
Swissprots	B2R811 P11182 Q5VVL8
Accessions	CAA48225 EAW72963 P11182 AK024946 AK303941 BAG64869 AK313191 BAG36008 BC016675 AAH16675 BC030002 BT007372 AAP36036 DA274670 J03208 AAA35589 M19301 AAA59200 M27093 AAA64512 X57677 X66785 CAA47285 XM_005270545 XP_005270602 XM_005270546 XP_005270603 XR_946560 NM_001918 NP_001909
Function	The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Within this complex, the catalytic function of this enzyme is to accept, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component.
Subcellular Location	Mitochondrion matrix.
Top Pathways	Valine, leucine and isoleucine degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DBT 293T Cell Transient Overexpression Lysate(Denatured) - H00001629-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

DBT overexpression lysate - LY419653 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

DBT 293 Cell Lysate - 409198 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

DBT Overexpression Lysate (Denatured) - H00001629-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

DBT Overexpression Lysate (Native) - NBL1-09735 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

DBT Over-expression Lysate Product - GWB-A41D01 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human DBT Knockdown Stable Cell Line - CSC-DC004051 from Creative biogene Category Cell Line Species Human

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