Gene Symbol | CCDC67 |
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Entrez Gene | 159989 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | coiled-coil domain containing 67 |
Other Description | coiled-coil domain-containing protein 67|deuterosome protein 1 |
Swissprots | Q8NEF1 Q05D60 Q96LL7 |
Accessions | EAW66898 EAW66899 EAW66900 Q05D60 AK058122 BAB71673 AK127973 BAC87213 BC017929 AAH17929 BC031247 AAH31247 BC050325 DB449834 XM_005273802 XP_005273859 XM_011542629 XP_011540931 XM_011542630 XP_011540932 XM_011542631 XP_011540933 XM_011542632 XP_011540934 XM_011542633 XP_011540935 XM_011542634 XP_011540936 XM_011542635 XP_011540937 XM_011542636 XP_011540938 XM_011542637 XP_011540939 XM_011542638 XP_011540940 XR_947796 XR_947797 XR_947798 XR_947799 XR_947800 NM_181645 NP_857596 |
Function | Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Note=Localizes to the deuterosome. {ECO:0000250}. |
CCDC67 (C-17) - sc-246185 from Santa Cruz Biotechnology
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CCDC67 (T-17) - sc-246184 from Santa Cruz Biotechnology
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Anti-CCDC67 antibody - ab81515 from Abcam
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Anti-CCDC67 antibody - ab102688 from Abcam
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Anti-CCDC67 Antibody (aa38-87) - LS-C82752 from LifeSpan Bioscience
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Anti-CCDC67 Antibody (aa113-162) - LS-C187193 from LifeSpan Bioscience
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CCDC67 Antibody - NBP1-91446 from Novus Biologicals
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CCDC67 Antibody - NBP1-93920 from Novus Biologicals
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CCDC67 Antibody - NBP2-15751 from Novus Biologicals
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CCDC67 Polyclonal Antibody - bs-8105R from Bioss
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Anti-CCDC67 antibody produced in rabbit - HPA010986 from Sigma-Aldrich
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Anti-CCDC67 antibody produced in rabbit - SAB2701469 from Sigma-Aldrich
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CCDC67 antibody - N-terminal region (ARP53397_P050) - ARP53397_P050 from Aviva Systems Biology
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CCDC67 Antibody - N-terminal region (ARP53398_P050) - ARP53398_P050 from Aviva Systems Biology
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CCDC67 antibody [C1C3] - GTX120422 from GeneTex
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CCDC67 antibody - 70R-3400 from Fitzgerald
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CCDC67 antibody - 24579-1-AP from Acris Antibodies
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CCDC67 antibody - H00159989-B01P from Acris Antibodies
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CCDC67 Antibody - 26-786 from ProSci
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CCDC67 antibody - 24579-1-AP from Proteintech Group
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CCDC67 - MBS271300 from MyBioSource
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CCDC67 Antibody - GWB-MT056B from Genway Biotech
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CCDC67 Polyclonal Antibody - PA5-31690 from Thermo Fisher Scientific
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CCDC67 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-8105R-A350 from Bioss
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CCDC67 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-8105R-A488 from Bioss
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